Cost-effectiveness of insulin degludec versus insulin glargine U100 in patients with type 1 and type 2 diabetes in Portugal: evidence from SWITCH 1&2 trials

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dc.contributor.authorDarbà, Josep
dc.contributor.authorAscanio, Meritxell
dc.contributor.authorCarvalho, Davide
dc.contributor.authorConde, Vasco
dc.contributor.authorPedersen, Kasper S.
dc.date.accessioned2020-06-10T08:05:43Z
dc.date.available2020-12-20T06:10:18Z
dc.date.issued2019-12-20
dc.date.updated2020-06-10T08:05:43Z
dc.description.abstractObjectives: To assess the cost-effectiveness of insulin degludec (degludec) versus insulin glargine (glargine) U100 from a Portuguese healthcare perspective using data from SWITCH 1 & 2 trials. - - - Methods: A short-term model estimated cost-effectiveness of degludec versus glargine U100 in type 1 diabetes (T1DM) basal bolus (B/B) and type 2 diabetes (T2DM) basal oral therapy (BOT) patients. The model captured hypoglycaemia rates and insulin dosing. Clinical outcomes were obtained from SWITCH 1 & 2. Disutilities related to hypoglycaemic events and insulin, needles and blood glucose tests costs were also included. Benefits were measured in QALYs. One-way and probabilistic sensitivity analyses were conducted (...)
dc.format.extent10 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec695776
dc.identifier.issn1646-3439
dc.identifier.urihttps://hdl.handle.net/2445/164999
dc.language.isoeng
dc.publisherCortex - Publicacoes Tecnicas e Cientificas
dc.relation.isformatofVersió postprint del document publicat a: http://www.revportdiabetes.com/rpd-dez-2019/
dc.relation.ispartofRevista Portuguesa de Diabetes, 2019, vol. 14, num. 4, p. 141-150
dc.rightscc-by-nc-nd (c) Cortex - Publicacoes Tecnicas e Cientificas, 2019
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es
dc.sourceArticles publicats en revistes (Economia)
dc.subject.classificationAnàlisi cost-benefici
dc.subject.classificationSalut pública
dc.subject.classificationDiabetis
dc.subject.classificationInsulina
dc.subject.classificationPortugal
dc.subject.otherCost effectiveness
dc.subject.otherPublic health
dc.subject.otherDiabetes
dc.subject.otherInsulin
dc.subject.otherPortugal
dc.titleCost-effectiveness of insulin degludec versus insulin glargine U100 in patients with type 1 and type 2 diabetes in Portugal: evidence from SWITCH 1&2 trials
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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