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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/216913
Quality of Life in Symptomatic Septal Perforation
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ObjectiveThe aim of this study is to investigate the impact of septal perforation (SP) on quality of life (QoL). SP is compared to the general population and patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) using the Sino-Nasal Outcome Test 22 (SNOT-22).MethodsProspective single-center study in a referral Rhinology Unit from January 2014 to March 2023.ResultsA total of 392 patients were included in three groups: controls (n = 141), CRSwNP (n = 118), and SP (n = 133). The mean score of the SNOT-22 was significantly higher in the CRSwNP group (42.4, SD = 24.4) and SP (46.5, SD = 22) compared to the control group (6.2, SD = 8.4). Scores by either items or domains were significantly higher in the CRSwNP and SP groups compared to the control group. There were no significant differences in the mean SNOT-22 between the CRSwNP and SP groups (p = 0.26; 95% CI -1.68-9.99). Domain-specific analysis of overall SNOT-22 scores revealed that patients with SP experienced higher levels of disturbances in sleep, function, and psychological domains (p ≤ 0.001).
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ALEGRE EDO, Berta, et al. Quality of Life in Symptomatic Septal Perforation. The Laryngoscope. 2024. Vol. 134, num. 11, pags. 4480-4487. ISSN 1531-4995. [consulted: 15 of June of 2026]. Available at: https://hdl.handle.net/2445/216913