Miniatura

Fitxers

GriffithKA.pdf (103.06 KB)

Tipus de document

Article

Versió

Versió acceptada

Data de publicació

2014-06

Tots els drets reservats

Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/126340

Correspondence between neurophysiological and clinical measurements of chemotherapy-induced peripheral neuropathy: secondary analysis of data from the CI-PeriNoms study

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1111/jns5.12064

Resum

Chemotherapy-induced peripheral neuropathy (CIPN) lacks standardized clinical measurement. The objective of the current secondary analysis was to examine data from the CIPN Outcomes Standardization (CI-PeriNomS) study for associations between clinical examinations and neurophysiological abnormalities. Logistic regression estimated the strength of associations of vibration, pin, and monofilament examinations with lower limb sensory and motor amplitudes. Examinations were classified as normal (0), moderately abnormal (1), or severely abnormal (2). Among 218 participants, those with class 1 upper extremity (UE) and classes 1 or 2 lower extremity (LE) monofilament abnormality were 2.79 (95% confidence interval [CI]: 1.28-6.07), 3.49 (95%CI: 1.61-7.55), and 4.42 (95%CI: 1.35-14.46) times more likely to have abnormal sural nerve amplitudes, respectively, compared to individuals with normal examinations. Likewise, those with class 2 UE and classes 1 or 2 LE vibration abnormality were 8.65 (95%CI: 1.81-41.42), 2.54 (95%CI: 1.19-5.41), and 7.47 (95%CI: 2.49-22.40) times more likely to have abnormal sural nerve amplitudes, respectively, compared to participants with normal examinations. Abnormalities in vibration and monofilament examinations are associated with abnormal sural nerve amplitudes and are useful in identifying CIPN.

Matèries

Quimioteràpia, Neurofisiologia

Matèries (anglès)

Chemotherapy, Neurophysiology

Citació

Col·leccions

Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

GRIFFITH, Kathleen a., DORSEY, Susan g., RENN, Cynthia l., ZHU, Shijun, JOHANTGEN, Mary e., CORNBLATH, David r., ARGYRIOU, Andreas a., CAVALETTI, Guido, MERKIES, Ingemar s. j., ALBERTI, Paola, POSTMA, Tjeerd j., ROSSI, Emanuela, FRIGENI, Barbara, BRUNA, Jordi, VELASCO, Roser, KALOFONOS, Haralabos p., PSIMARAS, Dimitri, RICARD, Damien, PACE, Andrea, GALIE, Edvina, BRIANI, Chiara, DALLA TORRE, Chiara, FABER, Catharina g., LALISANG, Roy i., BOOGERD, Willem, BRANDSMA, Dieta, KOEPPEN, Susanne, HENSE, Joerg, STOREY, Dawn j., KERRIGAN, Simon, SCHENONE, Angelo, FABBRI, Sabrina, VALSECCHI, Maria grazia, CI-PeriNomS Group. Correspondence between neurophysiological and clinical
measurements of chemotherapy-induced peripheral neuropathy:
secondary analysis of data from the CI-PeriNoms study. _Journal of the Peripheral Nervous System_. 2014. Vol. 19, núm. Issue 2, pàgs. 127-135. [consulta: 21 de desembre de 2025]. [Disponible a: https://hdl.handle.net/2445/126340]

Exportar metadades

JSON - METS

Compartir registre