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"Clown nose" as first manifestation of squamous cell carcinoma of the lung
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Abstract
Background: Skin metastases occur in 0.7% to 9% of all patients with cancer and are usually considered a late event in the evolution of most visceral carcinomas. The development of a nodular metastatic lesion on the nasal tip is known as clown nose sign.
Main observation: We report a 64-year-old man that developed a nodular lesion on his nasal tip as first manifestation of squamous lung carcinoma.
Conclusion: The biopsy of the cutaneous metastasis may be helpful to histopathologically confirm the suspected primary tumour avoiding invasive diagnostic procedures.
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MARCOVAL CAUS, Joaquim, et al. "Clown nose" as first manifestation of squamous cell carcinoma of the lung. Journal of Dermatological Case Reports. 2017. Vol. 11, num. 1, pags. 9-11. [consulted: 16 of August of 2026]. Available at: https://hdl.handle.net/2445/125260