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2014-08-26

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cc-by (c) Mejía-Lancheros, Cília et al., 2014
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/121115

Blood pressure values and depression in hypertensive individuals at high cardiovascular risk

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https://doi.org/10.1186/1471-2261-14-109

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BACKGROUND: Hypertension and depression are both important risk factors for cardiovascular diseases. Nevertheless, the association of blood pressure on and depression has not been completely established. This study aims to analyze whether depression may influence the control of blood pressure in hypertensive individuals at high cardiovascular risk. METHODS: Cross-sectional study, embedded within the PREDIMED clinical trial, of 5954 hypertensive patients with high cardiovascular risk factor profiles. The relationship between blood pressure control and depression was analyzed. A multivariate analysis (logistic and log-linear regression), adjusting for potential confounders (socio-demographic factors, body mass index, lifestyle, diabetes, dyslipidemia, and antihypertensive treatment), was performed. RESULTS: Depressive patients, with and without antidepressant treatment, had better blood pressure control (OR: 1.28, CI 95%: 1.06-1.55, and OR: 1.30, CI 95%: 1.03-1.65, respectively) than non-depressive ones. Regarding blood pressure levels, systolic blood pressure values (mmHg) were found to be lower in both treated and untreated depressive patients (Log coefficient Beta: -1.59, 95% CI: -0.50 to -2.69 and Log coefficient Beta: -3.49, 95% CI: -2.10 to -4.87, respectively). CONCLUSIONS: Among hypertensive patients at high cardiovascular risk, the control of blood pressure was better in those diagnosed with depression. TRIAL REGISTRATION: Unique identifier: ISRCTN35739639.

Matèries

Hipertensió, Depressió psíquica, Malalties cardiovasculars, Pressió sanguínia, Assaigs clínics

Matèries (anglès)

Hypertension, Mental depression, Cardiovascular diseases, Blood pressure, Clinical trials

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Articles publicats en revistes (Medicina)

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MEJÍA-LANCHEROS, Cília, ESTRUCH RIBA, Ramon, MARTÍNEZ-GONZÁLEZ, Miguel ángel, SALAS SALVADÓ, Jordi, CORELLA PIQUER, Dolores, GÓMEZ GRACIA, Enrique, FIOL SALA, Miguel, SANTOS, José manuel, FITÓ COLOMER, Montserrat, ARÓS, Fernando, SERRA MAJEM, Lluís, PINTÓ SALA, Xavier, BASORA, Josep, SORLÍ, José v., MUÑOZ PÉREZ, Miguel ángel. Blood pressure values and depression in hypertensive individuals at high cardiovascular risk. _BMC Cardiovascular Disorders_. 2014. Vol. 14, núm. 109. [consulta: 21 de gener de 2026]. ISSN: 1471-2261. [Disponible a: https://hdl.handle.net/2445/121115]

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