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2024-04

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/214862

Is long-term follow-up solely by imaging tests safe in non-operated pancreatic neuroendocrine tumors?

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https://doi.org/10.17235/reed.2023.9293/2022

Abstract

Introduction: the diagnosis of asymptomatic sporadic nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs) has increased significantly due to the widespread use of high-resolution imaging tests, which is why the most appropriate management at the time of diagnosis is the subject of debate, as is how to follow-up patients. Aims: the objective of this study was to analyze the frequency of imaging and endoscopic studies performed during long-term follow-up. Methods: a retrospective review was performed of a database collected between January 2008 and December 2020 of patients with an incidental diagnosis of small NF-PNETs; follow-up was closed in March 2023. The imaging tests performed at the time of diagnosis and long-term follow-up were recorded. Growing less than 1 mm per year has not been considered as a worrisome feature. Follow-up was performed through imaging tests, considering endoscopic cytology for lesions with a faster grow rate. Results: fifty-eight patients were included; the median age was 69 years. The initial mean size of the lesions studied was 12.79 mm (5-27). Follow-up was carried out only with computed tomography (CT) or magnetic resonance imaging (MRI). The initial size did not influence the behavior of the lesion in a statistically significant manner. Twenty-eight tumors (45 %) increased in size, with a growth equal to or less than 4 mm in 24 cases. The mean follow-up time was 82.41 months (12-164). No patient developed metastasis or died from PNET progression. Conclusions: the follow-up of neuroendocrine tumors of small size can be performed safely with only imaging tests.

Subject

Càncer de pàncrees, Diagnòstic per la imatge, Endoscòpia

Subject (English)

Pancreas cancer, Diagnostic imaging, Endoscopy

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Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citation

POLETTE, Daniela, et al. Is long-term follow-up solely by imaging tests safe in non-operated pancreatic neuroendocrine tumors?. Revista Española de Enfermedades Digestivas. 2024. Vol. 116, num. 4, pags. 209-215. ISSN 1130-0108. [consulted: 13 of August of 2026]. Available at: https://hdl.handle.net/2445/214862

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