Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study

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dc.contributor.authorTyrovolas, Stefanos
dc.contributor.authorPolychronopoulos, Evangelos
dc.contributor.authorMariolis, Anargiros
dc.contributor.authorPiscopo, Suzanne
dc.contributor.authorValacchi, Giuseppe
dc.contributor.authorMakri, Kornilia
dc.contributor.authorZeimbekis, Akis
dc.contributor.authorTyrovola, Dimitra
dc.contributor.authorBountziouka, Vassiliki
dc.contributor.authorGotsis, Efthimios
dc.contributor.authorMetallinos, George
dc.contributor.authorTur, Josep Antoni
dc.contributor.authorMatalas, Antonia Leda
dc.contributor.authorLionis, Christos
dc.contributor.authorHaro Abad, Josep Maria
dc.contributor.authorPanagiotakos, Demosthenes B.
dc.date.accessioned2018-10-08T17:14:47Z
dc.date.available2018-10-08T17:14:47Z
dc.date.issued2017-02-01
dc.date.updated2018-10-08T17:14:47Z
dc.description.abstractThe aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During 2005 to 2011, 2663 elders were voluntarily enrolled. A multidimensional successful aging index consisting of 10 components was used. Paternal and maternal longevity was defined as those older participants of whom both parents lived above the age of 90. The burden of CVD-related factors (CVD-RFs) was calculated as the total score of 4 major CVD-RFs (range 0-4). After adjustment, parental longevity was inversely associated with the burden of CVD-RFs ( P = .04). Moreover, parental longevity was positively associated with the older adults' successful aging score (β-coefficient [95% confidence interval]: .38 [0.06-0.71]). Parent's long living was revealed as an important factor for successful aging and for reduced CVD risk, suggesting that further research is needed in the genetic predisposition of longevity.
dc.format.extent26 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec667946
dc.identifier.issn0003-3197
dc.identifier.pmid27069110
dc.identifier.urihttps://hdl.handle.net/2445/125151
dc.language.isoeng
dc.publisherSAGE Publications
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1177/0003319716642140
dc.relation.ispartofAngiology, 2017, vol. 68, num. 2, p. 124-131
dc.relation.urihttps://doi.org/10.1177/0003319716642140
dc.rights(c) Tyrovolas, Stefanos et al., 2017
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Medicina)
dc.subject.classificationLongevitat
dc.subject.classificationMalalties cardiovasculars
dc.subject.classificationEpidemiologia genètica
dc.subject.otherLongevity
dc.subject.otherCardiovascular diseases
dc.subject.otherGenetic epidemiology
dc.titleIs parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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