Stereoselective Synthesis of (-)-Spicigerolide

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dc.contributor.authorGeorges, Yohan
dc.contributor.authorAriza Piquer, Xavier
dc.contributor.authorGarcía Gómez, Jordi
dc.date.accessioned2013-12-20T11:53:15Z
dc.date.available2013-12-20T11:53:15Z
dc.date.issued2009
dc.date.updated2013-12-20T11:53:15Z
dc.description.abstract(-)-Spicigerolide was enantioselectively synthesized from a protected (S)-lactaldehyde. The synthesis of the polyacetylated framework relied on two Zn-mediated stereoselective additions of alkynes to aldehydes as well as a regiocontrolled [3,3]-sigmatropic rearrangement of an allylic acetate. The pyranone moiety was constructed via ring-closing metathesis.
dc.format.extent16 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec565900
dc.identifier.issn0022-3263
dc.identifier.urihttps://hdl.handle.net/2445/48632
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.relation.isformatofVersió postprint del document publicat a: http://dx.doi.org/10.1021/jo8025753
dc.relation.ispartofJournal of Organic Chemistry, 2009, vol. 74, num. 5, p. 2008-2012
dc.relation.urihttp://dx.doi.org/10.1021/jo8025753
dc.rights(c) American Chemical Society , 2009
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Química Inorgànica i Orgànica)
dc.subject.classificationPlantes
dc.subject.classificationBotànica mèdica
dc.subject.classificationCitotoxicitat per mediació cel·lular
dc.subject.classificationCàncer
dc.subject.classificationEstereoquímica
dc.subject.classificationProductes naturals
dc.subject.classificationSíntesi orgànica
dc.subject.otherPlants
dc.subject.otherMedical botany
dc.subject.otherCell-mediated cytotoxicity
dc.subject.otherCancer
dc.subject.otherStereochemistry
dc.subject.otherNatural products
dc.subject.otherOrganic synthesis
dc.titleStereoselective Synthesis of (-)-Spicigerolide
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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