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2016-04-11

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cc-by-nc (c) Novick, Diego et al., 2016
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/111703

Impact of anxiety symptoms on outcomes of depression: an observational study in Asian patients

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https://doi.org/10.2147/NDT.S90134

Resum

OBJECTIVE: To investigate the impact of anxiety symptoms on depression outcomes in Asian patients with major depressive disorder (MDD) (n=714). METHODS: The 17-item Hamilton Depression Scale (HAMD-17), overall severity, somatic symptoms, and quality of life (QOL) (EuroQOL Questionnaire-5 Dimensions [EQ-5D]) were assessed at baseline and 3 months. Anxiety was measured using items 10 and 11 from the HAMD-17. Linear, tobit, and logistic multiple regression models analyzed the impact of anxiety symptoms on outcomes. Baseline anxiety was related to age and the presence of pain symptoms at baseline. RESULTS: Regression models showed that a higher level of anxiety was associated with a lower frequency of remission and lower QOL at 3 months. Patients with lower baseline anxiety symptoms had higher remission rates (odds ratio for each point of anxiety symptoms, 0.829 [95% confidence interval [CI]: 0.723-0.951]). Patients with higher levels of baseline anxiety had a lower QOL at 3 months (a decrease in EQ-5D tariff score for each point of anxiety symptoms, 0.023 [95% CI: 0.045-0.001]). CONCLUSION: In conclusion, the presence of anxiety symptoms negatively impacts the outcomes of depression.

Matèries

Ansietat, Depressió psíquica, Àsia

Matèries (anglès)

Anxiety, Mental depression, Asia

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Articles publicats en revistes (Medicina)

Citació

NOVICK, Diego, et al. Impact of anxiety symptoms on outcomes of depression: an observational study in Asian patients. Neuropsychiatric Disease And Treatment. 2016. Vol. 12, num. 795-800. ISSN 1176-6328. [consulted: 19 of August of 2026]. Available at: https://hdl.handle.net/2445/111703

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