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cc-by-nc (c) Novick, Diego et al., 2016
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/111703

Impact of anxiety symptoms on outcomes of depression: an observational study in Asian patients

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OBJECTIVE: To investigate the impact of anxiety symptoms on depression outcomes in Asian patients with major depressive disorder (MDD) (n=714). METHODS: The 17-item Hamilton Depression Scale (HAMD-17), overall severity, somatic symptoms, and quality of life (QOL) (EuroQOL Questionnaire-5 Dimensions [EQ-5D]) were assessed at baseline and 3 months. Anxiety was measured using items 10 and 11 from the HAMD-17. Linear, tobit, and logistic multiple regression models analyzed the impact of anxiety symptoms on outcomes. Baseline anxiety was related to age and the presence of pain symptoms at baseline. RESULTS: Regression models showed that a higher level of anxiety was associated with a lower frequency of remission and lower QOL at 3 months. Patients with lower baseline anxiety symptoms had higher remission rates (odds ratio for each point of anxiety symptoms, 0.829 [95% confidence interval [CI]: 0.723-0.951]). Patients with higher levels of baseline anxiety had a lower QOL at 3 months (a decrease in EQ-5D tariff score for each point of anxiety symptoms, 0.023 [95% CI: 0.045-0.001]). CONCLUSION: In conclusion, the presence of anxiety symptoms negatively impacts the outcomes of depression.

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NOVICK, Diego, MONTGOMERY, William, AGUADO, Jaume, PENG, Xiaomei, HARO ABAD, Josep maria. Impact of anxiety symptoms on outcomes of depression: an observational study in Asian patients. _Neuropsychiatric Disease And Treatment_. 2016. Vol. 12, núm. 795-800. [consulta: 9 de gener de 2026]. ISSN: 1176-6328. [Disponible a: https://hdl.handle.net/2445/111703]

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