Carregant...
Fitxers
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/122159
Effect of oral anticoagulants on the outcome of faecal immunochemical test
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
Background: We aimed to evaluate whether oral anticoagulants (OACs) alter faecal immunochemical test (FIT) performance in average-risk colorectal cancer (CRC) screening. Methods: Individuals aged 50-69 years were invited to receive one FIT sample (cutoff 75 ng ml-1) between November 2008 and June 2011. Results: Faecal immunochemical test was positive in 9.3% (21 out of 224) of users of OAC and 6.2% (365 out of 5821) of non-users (P-trend ¼ 0.07). The positive predictive value (PPV) for advanced neoplasia (AN) in non-users was 50.4% vs 47.6% in users (odds ratio, 0.70; 95% CI, 0.3-1.8; P ¼ 0.5). The PPV for AN in OAC more antiplatelets (aspirin or clopidogrel) was 75% (odds ratio, 2; 95% CI, 0.4-10.8; P ¼ 0.4). Conclusions: Oral anticoagulant did not significantly modify the PPV for AN in this population-based colorectal screening program. The detection rate of advanced adenoma was higher in the combination OAC more antiplatelets.
Matèries (anglès)
Citació
Citació
BUJANDA, Luis, SARASQUETA, Cristina, LANAS, Angel, QUINTERO, Enrique, CUBIELLA, Joaquín, HERNÁNDEZ, Vicent, MORILLAS, Juan d., PEREZ-FERNÁNDEZ, T., SALAS, D., ANDREU, Montserrat, CARBALLO, F., BESSA I CASERRAS, Xavier, PORTILLO, I., JOVER, Rodrigo, BALAGUER PRUNÉS, Francesc, COSME, Ángel, CASTELLS GARANGOU, Antoni. Effect of oral anticoagulants on the outcome of faecal immunochemical test. _British Journal of Cancer_. 2014. Vol. 110, núm. 5, pàgs. 1334-1337. [consulta: 25 de gener de 2026]. ISSN: 0007-0920. [Disponible a: https://hdl.handle.net/2445/122159]