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2023-02-19

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cc by (c) Hinchliffe, Alice et al, 2022
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/201089

Association of occupational heat exposure and colorectal cancer in the MCC-Spain study

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https://doi.org/10.5271/sjweh.4082

Resum

Objective Heat exposure and heat stress/strain is a concern for many workers. There is increasing interest in potential chronic health effects of occupational heat exposure, including cancer risk. We examined potential associations of occupational heat exposure and colorectal cancer (CRC) risk in a large Spanish multi-case- control study.Methods We analyzed data on 1198 histologically confirmed CRC cases and 2690 frequency-matched controls. The Spanish job-exposure matrix, MatEmEsp, was used to assign heat exposure estimates to the lifetime occupa-tions of participants. Three exposure indices were assessed: ever versus never exposed, cumulative exposure and duration (years). We estimated odds ratios (OR) and 95% confidence intervals (CI) using unconditional logistic regression adjusting for potential confounders.Results Overall, there was no association of ever, compared with never, occupational heat exposure and CRC (OR 1.09, 95% CI 0.92-1.29). There were also no associations observed according to categories of cumulative exposure or duration, and there was no evidence for a trend. There was no clear association of ever occupational heat exposure and CRC in analysis conducted among either men or women when analyzed separately. Positive associations were observed among women in the highest categories of cumulative exposure (OR 1.81, 95% CI 1.09-3.03) and duration (OR 2.89, 95% CI 1.50-5.59) as well as some evidence for a trend (P<0.05).Conclusion Overall, this study provides no clear evidence for an association between occupational heat exposure and CRC.

Matèries

Altes temperatures, Càncer colorectal

Matèries (anglès)

High temperatures, Colorectal cancer

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (ISGlobal)

Citació

HINCHLIFFE, Alice, KOGEVINAS, Manolis, MOLINA DE LA TORRE, Antonio josé, MORENO AGUADO, Víctor, ARAGONÈS SANZ, Núria, CASTAÑO VINYALS, Gemma, JIMÉNEZ MOLEÓN, José juan, GÓMEZ ACEBO, Inés, EDERRA, María, AMIANO, Pilar, MOLINA BARCELÓ, Ana, FERNÁNDEZ TARDÓN, Guillermo, ALGUACIL, Juan, CHIRLAQUE, María dolores, HERNÁNDEZ SEGURA, Natalia, PÉREZ GÓMEZ, Beatriz, POLLAN, Marina, TURNER, Michelle c.. Association of occupational heat exposure and colorectal cancer in the MCC-Spain study. _Scandinavian Journal of Work_. Environment & Health. Vol.  2023, núm. 49, pàgs. 3. [consulta: 24 de gener de 2026]. ISSN: 0355-3140. [Disponible a: https://hdl.handle.net/2445/201089]

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