Files
Document type
ArticleVersion
Published versionPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/183853
Porcine Protein Hydrolysates (PEPTEIVA(r)) Promote Growth and Enhance Systemic Immunity in Gilthead Sea Bream (Sparus aurata)
Journal Title
Director/Tutor
Journal ISSN
Volume Title
Related resource
Abstract
The effects of porcine plasma protein hydrolysate (PPH) on growth, feed efficiency, and immune responses was evaluated in Sparus aurata. Fish were fed two isoproteic (48% protein), isolipidic (17% fat), and isoenergetic diets (21.7 MJ/kg) diets, one of them containing 5% PPH at the expense of fishmeal. Both diets were tested for 92 days. A significant increase in growth was observed in fish fed the PPH diet in comparison to the control group (182.2 ± 4.4 vs. 173.8 ± 4.1 g), as well as an increase in feed intake without worsening FCR values. An ex vivo assay, with splenocytes incubated with lipopolysaccharide, was conducted to evaluate the cellular immune competence of fish. Genes involved in humoral immunity (lys, IgM), pro- (tnf-α, il-1β), and anti-inflammatory (tgf-β1, il10) cytokines were upregulated in the PPH group in comparison to the control group. The inclusion of PPH in diets enhanced the antibacterial capacity of skin mucus, as the co-culture of selected bacteria (E. coli, V. anguillarum, and P. anguilliseptica) with skin mucus indicated. The present results showed that the PPH in low fishmeal diets (2%) promoted growth and feed efficiency, as well as enhancing the immune response, which indicates that this is a safe and functional ingredient for aquafeeds.
Subject
Subject (English)
Citation
Citation
GISBERT CASAS, Enric, et al. Porcine Protein Hydrolysates (PEPTEIVA(r)) Promote Growth and Enhance Systemic Immunity in Gilthead Sea Bream (Sparus aurata). Animals. 2021. Vol. 11, num. 7, pags. 1-16. ISSN 2076-2615. [consulted: 8 of August of 2026]. Available at: https://hdl.handle.net/2445/183853