Adhesion G protein-coupled receptors

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dc.contributor.authorLangenhan, Tobias
dc.contributor.authorAnderson, Garret R.
dc.contributor.authorAraç, Demet
dc.contributor.authorAust, Gabriela
dc.contributor.authorAvila Zozaya, Monserrat
dc.contributor.authorBagger, Sofie Morsing
dc.contributor.authorBarth, Patrick
dc.contributor.authorBerndt, Sandra
dc.contributor.authorBlacklow, Stephen C.
dc.contributor.authorBlanco Redondo, Beatriz
dc.contributor.authorBoucard, Antony A.
dc.contributor.authorBridges, James
dc.contributor.authorBrodmerkel, Lara Sophie
dc.contributor.authorCaron, Kathleen M.
dc.contributor.authorYin, Kwan Chung
dc.contributor.authorDates, Andrew N.
dc.contributor.authorAraujo Farias, Virginea de
dc.contributor.authorToro Ruiz, Daniel del
dc.contributor.authorDuman, Joseph G.
dc.contributor.authorEngel, Felix B.
dc.contributor.authorFavara, David M.
dc.contributor.authorFormstone, Caroline J.
dc.contributor.authorFu, Chaoyu
dc.contributor.authorGarcia De Las Bayonas, Alain
dc.contributor.authorGeorgiadi, Anastasia
dc.contributor.authorGloriam, David E.
dc.contributor.authorHall, Randy A.
dc.contributor.authorHamann, Jörg
dc.contributor.authorHildebrand, Peter W.
dc.contributor.authorHsiao, Cheng-Chih
dc.contributor.authorHuang, Bill X.
dc.contributor.authorJavitch, Jonathan A.
dc.contributor.authorKim, Hee-Yong
dc.contributor.authorKittel, Robert J.
dc.contributor.authorKleinau, Gunnar
dc.contributor.authorLeduc, Richard
dc.contributor.authorLiebscher, Ines
dc.contributor.authorLin, Hsi-Hsien
dc.contributor.authorLinnert, Joshua
dc.contributor.authorLudwig, Marie Gabrielle
dc.contributor.authorMartinelli, David C.
dc.contributor.authorMathiasen, Signe
dc.contributor.authorMatúš, Daniel
dc.contributor.authorMelkumyan, Mariam
dc.contributor.authorMoreno Salinas, Ana L.
dc.contributor.authorMulder, Jan
dc.contributor.authorNash, Michael
dc.contributor.authorPal, Kasturi
dc.contributor.authorPederick, Daniel T.
dc.contributor.authorPerry Hauser, Nicole A.
dc.contributor.authorPiao, Xianhua
dc.contributor.authorPing, Yu-Qi
dc.contributor.authorPlacantonakis, Dimitris G.
dc.contributor.authorPohl, Fabian
dc.contributor.authorPrömel, Simone
dc.contributor.authorRosenkilde, Mette M.
dc.contributor.authorSabbagh, Laurent
dc.contributor.authorSando, Richard C.
dc.contributor.authorScheerer, Patrick
dc.contributor.authorSchöneberg, Torsten
dc.contributor.authorSeiradake, Elena
dc.contributor.authorSelcho, Mareike
dc.contributor.authorSeufert, Florian
dc.contributor.authorSingh, Abhishek Kumar
dc.contributor.authorSkiniotis, Georgios
dc.contributor.authorSpiess, Katja
dc.contributor.authorSträter, Norbert
dc.contributor.authorStrutt, David
dc.contributor.authorSüdhof, Thomas C.
dc.contributor.authorSun, Jinpeng
dc.contributor.authorTall, Gregory G.
dc.contributor.authorThor, Doreen
dc.contributor.authorTilley, Douglas G.
dc.contributor.authorTolias, Kimberley F.
dc.contributor.authorVallon, Mario
dc.contributor.authorMeir, Erwin G. Van
dc.contributor.authorVanhollebeke, Benoit
dc.contributor.authorWiggin, Giselle R.
dc.contributor.authorWolfrum, Uwe
dc.contributor.authorYan, Jie
dc.contributor.authorZaidman, Nathan A.
dc.contributor.authorZou, Yimin
dc.contributor.authorScholz, Nicole
dc.date.accessioned2026-04-09T16:49:32Z
dc.date.available2026-04-09T16:49:32Z
dc.date.issued2026-05-01
dc.date.updated2026-04-09T16:49:32Z
dc.description.abstractAdhesion G protein-coupled receptors (aGPCRs) constitute a structurally and functionally distinct group within the superfamily of GPCRs. In 2015, the International Union of Pharmacology invited the Adhesion GPCR Consortium to publish a comprehensive review about aGPCRs and to establish a unified nomenclature. Since then, substantial progress has been made in delineating the biological roles, molecular architecture, biochemical properties, expression profiles, ligand repertoire, and activation and signaling strategies of aGPCRs. Commensurate with these advances, their relevance to human pathophysiology has become increasingly evident. In a coordinated effort, the Adhesion GPCR Consortium has reviewed recent progress in the field and provides a comprehensive assessment of the current understanding of aGPCR biology here. This includes a focus on human and mammalian aGPCRs, their evolutionary origins, methodological approaches and model systems for their investigation, as well as emerging approaches for their therapeutic targeting
dc.format.extent56 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec768843
dc.identifier.issn0031-6997
dc.identifier.pmid41895071
dc.identifier.urihttps://hdl.handle.net/2445/228778
dc.language.isoeng
dc.publisherElsevier
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.pharmr.2026.100116
dc.relation.ispartofPharmacological Reviews, 2026, vol. 78, num. 3, 100116
dc.relation.urihttps://doi.org/10.1016/j.pharmr.2026.100116
dc.rightscc-by (c) Langenhan, Tobias et al., 2026
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceArticles publicats en revistes (Biomedicina)
dc.subject.classificationProteïnes G
dc.subject.classificationFixació de proteïnes
dc.subject.classificationEstructura molecular
dc.subject.otherG Proteins
dc.subject.otherProtein binding
dc.subject.otherMolecular structure
dc.titleAdhesion G protein-coupled receptors
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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