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2018-03-01

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cc by (c) Fourcade et al., 2018
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/172608

SIRT2 in age-related neurodegenerative disorders

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Abstract

Sirtuin 2 (SIRT2) is one of seven members of the NAD+-dependent histone deacetylases (HDAC) family of proteins. Sirtuins play diverse roles in cellular metabolism and the aging process. SIRT2 is located in the nucleus, cytoplasm, and mitochondria, is highly expressed in the central nervous system (CNS), and has been reported to regulate a variety of processes including oxidative stress, genome integrity, and myelination [1].

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https://doi.org/10.18632/aging.101397

Subject

Malalties neurodegeneratives, Envelliment

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Neurodegenerative Diseases, Aging

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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FOURCADE, Stéphane, OUTEIRO, Tiago F. and PUJOL ONOFRE, Aurora. SIRT2 in age-related neurodegenerative disorders. Aging-us. 2018. Vol. 10, num. 3, pags. 295-296. [consulted: 14 of October of 2026]. Available at: https://hdl.handle.net/2445/172608

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