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Accepted version

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2013-03-11

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/108109

First Enantioselective Synthesis of Tetracyclic Intermediates en route to Madangamine D

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https://doi.org/10.1039/C3CC41104D

Abstract

The enantioselective synthesis of advanced tetracyclic precursors of madangamine D, bearing rings ABCD of this alkaloid, is reported. The saturated 14-membered ring is assembled from functionalized diazatricyclic intermediates 10 following either ring-closing metathesis or macrolactamization strategies.

Subject

Alcaloides, Compostos heterocíclics, Estructura molecular

Subject (English)

Alkaloids, Heterocyclic compounds, Molecular structure

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Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

Citation

AMAT TUSÓN, Mercedes, et al. First Enantioselective Synthesis of Tetracyclic Intermediates en route to Madangamine D. Chemical Communications. 2013. Vol. 49, num. 30, pags. 3149-3151. ISSN 1359-7345. [consulted: 12 of June of 2026]. Available at: https://hdl.handle.net/2445/108109

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