Generation of the induced pluripotent stem cell line ESi108-A from a familial atrial fibrillation patient

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dc.contributor.authorMartínez Moreno, Rebecca
dc.contributor.authorPérez Serra, Alexandra
dc.contributor.authorSelga, Elisabet
dc.contributor.authorCarreras, David
dc.contributor.authorAran, Begoña
dc.contributor.authorKuebler, Bernd
dc.contributor.authorScornik, Fabiana S.
dc.contributor.authorPérez, Guillermo J.
dc.contributor.authorBrugada, Ramon
dc.date.accessioned2025-12-16T11:38:24Z
dc.date.available2025-12-16T11:38:24Z
dc.date.issued2023-10-31
dc.date.updated2025-12-05T11:44:12Z
dc.description.abstractTissue-specific cells differentiated from patient-derived human induced pluripotent stem cells (hiPSC) are a relevant cellular model to study several diseases. We obtained a hiPSC line from skin fibroblasts of a patient affected by familial atrial fibrillation by nucleofection of non-integrating episomal vectors. The resulting hiPSC line displays a normal karyotype, expresses pluripotency surface markers and pluripotency genes, and differentiates into cells of the 3 germ layers. Therefore, it represents a reliable model to study the disease in a physiologically relevant cellular environment.
dc.format.extent4 p.
dc.format.mimetypeapplication/pdf
dc.identifier.issn1873-5061
dc.identifier.pmid37922745
dc.identifier.urihttps://hdl.handle.net/2445/224973
dc.language.isoeng
dc.publisherElsevier BV
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.scr.2023.103239
dc.relation.ispartofStem Cell Research, 2023, vol. 73
dc.relation.urihttps://doi.org/10.1016/j.scr.2023.103239
dc.rightscc-by (c) Martínez Moreno, Rebecca et al., 2023
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceArticles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
dc.subject.classificationEpigènesi
dc.subject.classificationPatologia cel·lular
dc.subject.classificationCèl·lules mare embrionàries
dc.subject.otherEpigenesis
dc.subject.otherCellular pathology
dc.subject.otherEmbryonic stem cells
dc.titleGeneration of the induced pluripotent stem cell line ESi108-A from a familial atrial fibrillation patient
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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