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Item embargoed until 2027-01-12

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2025-01-13

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cc-by-nc-nd (c) Elsevier B.V., 2025
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/221145

Concentrated Cognitive-Behavior Therapy for Unmedicated Children and Adolescents With Obsessive-Compulsive Disorder in Routine Clinical Care: A Randomized Controlled Trial With a 6-Month Naturalistic Follow-up

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https://doi.org/https://doi.org/10.1016/j.beth.2025.01.001

Abstract

Cognitive-behavior therapy (CBT) is effective for obsessive-compulsive disorder (OCD). Because CBT requires significant time and resources, there is an increased interest in developing shorter formats of CBT for OCD (i.e., fewer sessions or in less time). We conducted a randomized single-blind controlled trial to investigate the effectiveness of concentrated CBT (co-CBT; 20 hours of therapist time across one month) compared to a waiting list (WL) in 30 unmedicated children and adolescents with OCD aged 7-17 in routine clinical care. Co-CBT was superior to the WL in reducing OCD symptom severity at post-treatment (primary endpoint; Cohen’s d =1.76) and these results were maintained through the end of a naturalistic six-month followup.

Participants initially randomized to the WL were offered co-CBT at the end of the trial and post-hoc analyses showed that they had similar improvements to those initially randomized to co-CBT. In post-hoc predictor analyses, participants aged 7-12, compared to those aged 13-17, and those with higher baseline OCD severity showed better post-treatment outcomes. Co-CBT is an effective intervention for unmedicated children and adolescents with OCD in routine clinical care. Studies including more robust control groups and larger samples are needed to replicate and expand thesefindings. Trial registration number: NCT04042038

Subject

Neurosi obsessiva, Adolescents, Infants, Assaigs clínics

Subject (English)

Obsessive-compulsive disorder, Teenagers, Children, Clinical trials

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Articles publicats en revistes (Medicina)

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HERMIDA BARROS, Laura, et al. Concentrated Cognitive-Behavior Therapy for Unmedicated Children and Adolescents With Obsessive-Compulsive Disorder in Routine Clinical Care: A Randomized Controlled Trial With a 6-Month Naturalistic Follow-up. Behavior Therapy. 2025. Vol. 56, num. 1. ISSN 0005-7894. [consulted: 8 of June of 2026]. Available at: https://hdl.handle.net/2445/221145

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