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Diagnosis of Trypanosoma cruzi Infection Status using Saliva of Infected Subjects
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Chagas disease has the highest prevalence of any parasitic
disease in the Americas, affecting 6-7 million people.
Conventional diagnosis requires a well-equipped laboratory with
experienced personnel. The development of new diagnostic tools
that are easy to use and adapted to the reality of affected
populations and health systems is still a significant challenge.
The main objective of this study was to measure Trypanosoma
cruzi infection status using saliva samples of infected
subjects. Blood and saliva samples from 20 T. cruzi-seropositive
individuals and 10 controls were tested for T. cruzi infection
using two different commercial serological tests. We have shown
that detection of T. cruzi infection is possible using saliva
samples, supporting the potential use of saliva to diagnose
Chagas disease in humans. This method could provide a simple,
low-cost but effective tool for the diagnosis of T. cruzi
infection. Its noninvasive nature makes it particularly well
suited for endemic areas.
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CORTÉS SERRA, Núria, et al. Diagnosis of Trypanosoma cruzi Infection Status using Saliva of
Infected Subjects. American Journal of Tropical Medicine and Hygiene. 2018. ISSN 0002-9637. [consulted: 3 of August of 2026]. Available at: https://hdl.handle.net/2445/120237