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Article

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Accepted version

Publication date

2013

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/43586

Total synthesis of (-)-isoavenaciolide

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Related resource

http://dx.doi.org/10.1021/jo302598h

Abstract

An enantioselective approach to (-)-isoavenaciolide was achieved starting from 1- undecyn-3-ol. The synthesis relied upon the preparation of a chiral 4-silyloxy-2-alkenylborane by hydroboration of a protected 2,3-allenol and subsequent stereoselective addition to 2- thiophenecarboxaldehyde

Subject

Biomolècules, Productes naturals, Síntesi asimètrica, Medicaments antibacterians, Fungicides

Subject (English)

Biomolecules, Natural products, Asymmetric synthesis, Antibacterial agents, Fungicides

Citation

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Articles publicats en revistes (Química Inorgànica i Orgànica)

Citation

SANTOS, David, et al. Total synthesis of (-)-isoavenaciolide. Journal of Organic Chemistry. 2013. Vol. 78, num. 4, pags. 1519-1524. ISSN 0022-3263. [consulted: 11 of August of 2026]. Available at: https://hdl.handle.net/2445/43586

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