Analysis of slow waves in the cerebral cortex during aging

Güell Brugués, Arnau

Analysis of slow waves in the cerebral cortex during aging

dc.contributor.advisor	Gutiérrez Gálvez, Agustín
dc.contributor.advisor	Sánchez-Vives, María Victoria
dc.contributor.advisor	Manasanch Berengué, Arnau
dc.contributor.author	Güell Brugués, Arnau
dc.date.accessioned	2023-06-21T12:57:18Z
dc.date.available	2023-06-21T12:57:18Z
dc.date.issued	2023-06-12
dc.description	Treballs Finals de Grau d'Enginyeria Biomèdica. Facultat de Medicina i Ciències de la Salut. Universitat de Barcelona. Curs: 2022-2023. Tutor/Director: Gutiérrez Gálvez, Agustí, Sánchez Vives, Maria V., Manasanch Berengué, Arnau	ca
dc.description.abstract	Slow oscillations, which are the default mode of the cortex and the main oscillation in slow-wave sleep, may be affected by aging. In this project, aging effect on the properties of the cortical slow oscillation is studied in 3, 7, 15 and 20 months of age sedated mice with Slowpy, a specialized pipeline for slow oscillations. Results show that aging affects the duration of Ups and Downs, as they slightly decrease with age, as well as the is an increase of the firing rate of the Up states with age. These effects can be explained by several biological and physiological reasons, such as changes in neuronal excitability and network connectivity. However, the effects of aging in functional connectivity remain unclear with this project, as this relationship has not been directly addressed in this study.	ca
dc.format.extent	39 p.
dc.format.mimetype	application/pdf
dc.identifier.uri	https://hdl.handle.net/2445/199610
dc.language.iso	eng	ca
dc.rights	cc-by-nc-nd (c) Güell Brugués, Arnau, 2023
dc.rights.accessRights	info:eu-repo/semantics/openAccess	ca
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/es/	*
dc.source	Treballs Finals de Grau (TFG) - Enginyeria Biomèdica
dc.subject.classification	Enginyeria biomèdica
dc.subject.classification	Ones
dc.subject.classification	Treballs de fi de grau
dc.subject.classification	Escorça cerebral
dc.subject.classification	Xarxes neuronals (Neurobiologia)
dc.subject.classification	Edats de la vida
dc.subject.other	Biomedical engineering
dc.subject.other	Waves
dc.subject.other	Bachelor's theses
dc.subject.other	Cerebral cortex
dc.subject.other	Neural networks (Neurobiology)
dc.subject.other	Human life cycle
dc.title	Analysis of slow waves in the cerebral cortex during aging	ca
dc.type	info:eu-repo/semantics/bachelorThesis	ca