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2015-01-15

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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/127956

One-year outcome following biological or mechanical valve replacement for infective endocarditis

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https://doi.org/10.1016/j.ijcard.2014.10.125

Resum

Background: Nearly half of patients require cardiac surgery during the acute phase of infective endocarditis (IE). We describe the characteristics of patients according to the type of valve replacement (mechanical or biological), and examine whether the type of prosthesis was associated with in-hospital and 1-year mortality. Methods and results: Among 5591 patients included in the International Collaboration on Endocarditis Prospective Cohort Study, 1467 patients with definite IE were operated on during the active phase and had a biological (37%) or mechanical (63%) valve replacement. Patients who received bioprostheses were older (62 vs 54 years), more often had a history of cancer (9% vs 6%), and had moderate or severe renal disease (9% vs 4%); proportion of health care-associated IE was higher (26% vs 17%); intracardiac abscesses were more frequent (30% vs 23%). In-hospital and 1-year death rates were higher in the bioprosthesis group, 20.5% vs 14.0% (p = 0.0009) and 25.3% vs 16.6% (p < .0001), respectively. In multivariable analysis, mechanical prostheses were less commonly implanted in older patients (odds ratio: 0.64 for every 10 years), and in patients with a history of cancer (0.72), but were more commonly implanted in mitral position (1.60). Bioprosthesis was independently associated with 1-year mortality (hazard ratio: 1.298). Conclusions: Patients with IE who receive a biological valve replacement have significant differences in clinical characteristics compared to patients who receive a mechanical prosthesis. Biological valve replacement is independently associated with a higher in-hospital and 1-year mortality, a result which is possibly related to patient characteristics rather than valve dysfunction.

Matèries

Endocarditis, Cirurgia, Pròtesis valvulars cardíaques

Matèries (anglès)

Endocarditis, Surgery, Heart valve prosthesis

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

HERAS, Magda, ALMELA, M. (manel), ARMERO, Yolanda, AZQUETA, Manuel, CASTAÑEDA, Ximena, CERVERA, Carlos, RIO, Ana del, FALCES SALVADOR, Carles, GARCÍA DE LA MÀRIA, Cristina, FITA, Guillermina, GATELL, José m., LLOPIS PÉREZ, Jaime, MARCO REVERTÉ, Francesc, MESTRES LUCIO, Carlos-alberto, MIRÓ MEDA, José m. (josé maría), MORENO CAMACHO, Ma. asunción, NINOT I SUGRAÑES, Josep maria, PARÉ, Carlos, PERICÀS, Juan m., RAMIREZ, José, ROVIRA, Irene, SITGES CARREÑO, Marta, ANGUERA CAMÓS, Ignasi, Endocarditis Prospective Cohort Study (ICE-PCS) Investigators. One-year outcome following biological or mechanical valve replacement for infective endocarditis. _International Journal of Cardiology_. 2015. Vol. 178, núm. 117-123. [consulta: 13 de desembre de 2025]. ISSN: 0167-5273. [Disponible a: https://hdl.handle.net/2445/127956]

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