Miniatura

Fitxers

ChristakoudiS.pdf (2.39 MB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2020-09-03

Llicència de publicació

cc by (c) Christakoudi, Sofia et al., 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/173423

A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1038/s41598-020-71302-5

Resum

Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proportional hazards models adjusted for other risk factors. During a mean follow-up of 16.1 years, 38,178 participants died. Combining in one model BMI and a strongly correlated waist index altered the association patterns with mortality, to a predominantly negative association for BMI and a stronger positive association for the waist index, while combining BMI with the uncorrelated A Body Shape Index (ABSI) preserved the association patterns. Sex-specific cohort-wide quartiles of waist indices correlated with BMI could not separate high-risk from low-risk individuals within underweight (BMI<18.5 kg/m(2)) or obese (BMI30 kg/m(2)) categories, while the highest quartile of ABSI separated 18-39% of the individuals within each BMI category, which had 22-55% higher risk of death. In conclusion, only a waist index independent of BMI by design, such as ABSI, complements BMI and enables efficient risk stratification, which could facilitate personalisation of screening, treatment and monitoring.

Matèries

Obesitat, Mortalitat, Factors de risc en les malalties

Matèries (anglès)

Obesity, Mortality, Risk factors in diseases

Citació

Col·leccions

Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
<b>Publicacions de projectes de recerca finançats per la UE</b>

Citació

CHRISTAKOUDI, Sofia, TSILIDIS, Konstantinos k., MULLER, David c., FREISLING, Heinz, WEIDERPASS, Elisabete, OVERVAD, Kim, SODERBERG, Stefan, HAGGSTROM, Christel, PISCHON, Tobias, DAHM, Christina c., ZHANG, Jie, TJØNNELAND, Anne, HALKJÆR, Jytte, MACDONALD, Conor, BOUTRON-RUAULT, Marie-christine, MANCINI, Francesca romana, KÜHN, Tilman, KAAKS, Rudolf, SCHULZE, Matthias b., TRICHOPOULOU, Antonia, KARAKATSANI, Anna, PEPPA, Eleni, MASALA, Giovanna, PALA, Valeria, PANICO, Salvatore, TUMINO, Rosario, SACERDOTE, Carlotta, QUIRÓS, José ramón, AGUDO, Antonio, SÁNCHEZ, María josé, CIRERA, Lluís, BARRICARTE, Aurelio, AMIANO, Pilar, MEMARIAN, Ensieh, SONESTEDT, Emily, BUENO DE MESQUITA, H. bas, MAY, Anne m., KHAW, Kay‑tee, WAREHAM, Nicholas j., TONG, Tammy y. n., HUYBRECHTS, Inge, NOH, Hwayoung, AGLAGO, Elom k., ELLINGJORD-DALE, Merete, WARD, Heather a., AUNE, Dagfinn, RIBOLI, Elio. A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity: results from a large European cohort. _Scientific Reports_. 2020. Vol. 10, núm. 10, pàgs. 14541. [consulta: 20 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/173423]

Exportar metadades

JSON - METS

Compartir registre