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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/218527
Backtracking NOM1::ETV6 fusion to neonatal pathogenesis of t(7;12) (q36;p13) infant AML.
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This work demonstrated the prenatal origin of the translocation t(7;12) giving rise to the ETV6-NOM1 fusion protein, in a 5-month-old patient with acute myeloblastic leukemia using an umbilical cord blood (CB) sample from the patient stored at birth. Our findings revealed the presence of a specific t(7;12)/ETV6-NOM1 fusion in both CD34+ hematopoietic stem/progenitor cells and in the CD34-CD33+ myeloid cellular compartment isolated from the patient’s umbilical CB.
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BOUSQUETS MUÑOZ, Pablo, et al. Backtracking NOM1::ETV6 fusion to neonatal pathogenesis of t(7;12) (q36;p13) infant AML. Leukemia. 2024. Vol. 38, num. 1808-1812. ISSN 0887-6924. [consulted: 11 of October of 2026]. Available at: https://hdl.handle.net/2445/218527