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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/126415
Measuring apoptosis at the single cell level
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The use of live cell microscopy has made a number of contributions to the study of apoptosis. Many of the tools and techniques are available that allow us to image the key events that occur during cell death including mitochondrial outer membrane permeabilization, mitochondrial transmembrane potential changes, translocation of Bcl-2 family members, caspase activation, phosphatidylserine flip and plasma membrane rupture. We discuss these techniques here and highlight the advantages and drawbacks of using such approaches to study apoptosis. (C) 2007 Elsevier Inc. All rights reserved.
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BOUCHIER-HAYES, Lisa, et al. Measuring apoptosis at the single cell level. Methods. 2008. Vol. 44, num. 3, pags. 222-228. [consulted: 14 of August of 2026]. Available at: https://hdl.handle.net/2445/126415