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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/193912
Using the emotional functioning in clinical practice to detect psychological distress in patients with advanced thoracic and colorectal cancer
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Purpose: Patients with advanced cancer suffer significant decline of their psychological state. A rapid and reliable evaluation of this state is essential to detect and treat it and improve quality of life. The aim was to probe the usefulness of the emotional function (EF) subscale of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 (EF-EORTC-QLQ-C30) to assess psychological distress in cancer patients. Methods: This is a multicenter, prospective, observational study involving 15 Spanish hospitals. Patients diagnosed with unresectable advanced thoracic or colorectal cancer were included. Participants completed the Brief Symptom Inventory 18 (BSI-18), the current the gold standard, and the EF-EORTC-QLQ-C30 to assess their psychological distress prior to initiating systemic antineoplastic treatment. Accuracy, sensitivity, positive predictive value (PPV), specificity, and negative predictive value (NPV) were calculated. Results: The sample comprised 639 patients: 283 with advanced thoracic cancer and 356 with advanced colorectal cancer. According to the BSI scale, 74% and 66% displayed psychological distress with an EF-EORTC-QLQ-C30 accuracy of 79% and 76% in detecting psychological distress in individuals with advanced thoracic and colorectal cancer, respectively. Sensitivity was 79 and 75% and specificity was 79 and 77% with a PPV of 92 and 86% and a NPV of 56 and 61% (scale cut-off point, 75) for patients with advanced thoracic and colorectal cancer, respectively. The mean AUC for thoracic cancer was 0.84 and, for colorectal cancer, it was 0.85. Conclusion: This study reveals that the EF-EORTC-QLQ-C30 subscale is a simple and effective tool for detecting psychological distress in people with advanced cancer.
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RODRÍGUEZ-GONZÁLEZ, Adán, HERNÁNDEZ SAN GIL, Raquel, CRUZ-CASTELLANOS, Patricia, FERNÁNDEZ MONTES, Ana, CASTILLO-TRUJILLO, Oscar, MUÑOZ, Maria del mar, CANO, Juana maría, CORRAL, María-josé, ESTEBAN, Emilio, JIMÉNEZ FONSECA, Paula, CALDERÓN GARRIDO, Caterina. Using the emotional functioning in clinical practice to detect psychological distress in patients with advanced thoracic and colorectal cancer. _Health And Quality Of Life Outcomes_. 2023. Vol. 21, núm. 15. [consulta: 21 de gener de 2026]. ISSN: 1477-7525. [Disponible a: https://hdl.handle.net/2445/193912]