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Optimizing (Bio) Catalysis with Liquid-Liquid Phase Separation Systems

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dc.contributor.authorReis, David Q. P.
dc.contributor.authorCalvário, Joana
dc.contributor.authorChibeles, Inês
dc.contributor.authorKumar, Mohit
dc.contributor.authorPina, Ana S.
dc.date.accessioned2026-04-09T13:36:38Z
dc.date.available2026-04-09T13:36:38Z
dc.date.issued2025-11-14
dc.date.updated2026-04-09T13:36:38Z
dc.description.abstractMembraneless organelles, also known as biomolecular condensates, lack a surrounding membrane and are formed through liquid-liquid phase separation (LLPS). This process enhances reaction efficiency by compartmentalizing and concentrating reactants. Coacervates, a class of condensates, provide promising synthetic alternatives for improving enzymatic reactions. This review examines how LLPS enhances reaction efficiency in both natural and artificial systems, explores the design principles of coacervate-based artificial organelles employed in (bio)catalysis, and discusses challenges and future directions for leveraging LLPS in catalysis.
dc.format.extent23 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec764752
dc.identifier.urihttps://hdl.handle.net/2445/228769
dc.language.isoeng
dc.publisherWiley-VCH
dc.relation.isformatofVersió publicada del document publicat a: https://doi.org/10.1002/syst.202400089
dc.relation.ispartofChemSystemsChem, 2025, vol. 7, p. 1-23
dc.relation.urihttps://doi.org/10.1002/syst.202400089
dc.rightscc-nc-nd-by (c) Reis, David Q. P. et al., 2025
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.uricc by-nc-nd https://creativecommons.org/li censes/by-nc-nd/4.0/
dc.sourceArticles publicats en revistes (Química Inorgànica i Orgànica)
dc.titleOptimizing (Bio) Catalysis with Liquid-Liquid Phase Separation Systems
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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Articles publicats en revistes (Química Inorgànica i Orgànica)