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cc-by (c)  Lazarus Jeffrey V. et al., 2023
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/219345

Combined COVID-19 vaccination and hepatitis C virus screening intervention in marginalised populations in Spain

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Background: COVID-19 has hindered hepatitis C virus (HCV) and HIV screening, particularly in marginalised groups, who have some of the highest rates of these conditions and lowest rates of COVID-19 vaccination. We assessed the acceptability of combining HCV testing with COVID-19 vaccination in a centre for addiction services (CAS) in Barcelona and a mobile testing unit (MTU) in Madrid, Spain. Methods: From 28/09/2021 to 30/06/2022, 187 adults from marginalised populations were offered HCV antibody (Ab) testing along with COVID-19 vaccination. If HCV Ab+, they were tested for HCV-RNA. MTU participants were also screened for HIV. HCV-RNA+ and HIV+ participants were offered treatment. Data were analysed descriptively. Results: Findings show how of the 86 CAS participants: 80 (93%) had been previously vaccinated for COVID-19, of whom 72 (90%) had the full first round schedule; none had a COVID-19 vaccine booster and all received a COVID-19 vaccine; 54 (62.8%) were tested for HCV Ab, of whom 17 (31.5%) were positive, of whom all were tested for HCV-RNA and none were positive. Of the 101 MTU participants: none had been vaccinated for COVID-19 and all received a COVID-19 vaccine; all were tested for HCV Ab and HIV and 15 (14.9%) and 9 (8.9%) were positive, respectively; of those HCV Ab+, 9 (60%) were HCV-RNA+, of whom 8 (88.9%) have started treatment; 5 (55.6%) of those HIV+ had abandoned antiretroviral therapy, of whom 3 (60%) have re-started it. Conclusions: The intervention was accepted by 54 (62.8%) CAS participants and all MTU participants and can be used in marginalised communities.

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LAZARUS, Jeffrey v., VILLOTA RIVAS, Marcela, RYAN MURÚA, Pablo, BUTI, Maria, GRAU LÓPEZ, Lara, CUEVAS, Guillermo, ESPADA, José luis, MORÓN, William, PALMA ÁLVAREZ, R. felipe, FELD, Jordan j., VALENCIA, Jorge. Combined COVID-19 vaccination and hepatitis C virus screening intervention in marginalised populations in Spain. _Communications medicine_. 2023. Vol. 3, núm. 1. [consulta: 24 de novembre de 2025]. ISSN: 2730-664X. [Disponible a: https://hdl.handle.net/2445/219345]

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