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2021-02-01

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cc-by (c) Iurina, Elena et al., 2021
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/230149

Personality changes in patients with refractory epilepsy after surgical treatment: A systematic review

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https://doi.org/10.1016/j.seizure.2020.12.026

Resum

Purpose We aimed to conduct a systematic review to evaluate the personality changes in adult patients with drug-resistant epilepsy following surgical treatment. Methods A systematic review was conducted using the Preferred Reporting Items of Systematic Reviews and MetaAnalyses (PRISMA) statement. We searched PubMed, Medline databases, and the Cochrane Controlled Trials Register, with search terms ‘personality’, ‘epilepsy’, and ‘surgery’. Results Eleven studies were selected. In 7 out of 11 studies, personality changes were more adaptive, with patients experiencing decreased neuroticism, impulsivity, hypochondriasis, psychasthenia. One study showed increased emotional lability. The remainder of the studies showed no changes in personality dimensions. Changes in personality differed according to the localization of the epileptogenic area, depended on seizure status after treatment and duration of follow-up. Seizure freedom as an outcome of surgical treatment influenced the existence of personality changes, and their severity. Adaptive personality changes could be seen from early follow-up assessments even in patients who were not seizure-free, though further follow-ups showed that improvements after 1–2 years were specific to seizure-free patients.

Matèries

Epilèpsia, Epilepsy, Trastorns de la personalitat

Matèries (anglès)

Personality disorders

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Articles publicats en revistes (Fonaments Clínics)

Citació

IURINA, Elena, BAILLES, Eva and PINTOR PÉREZ, Luis. Personality changes in patients with refractory epilepsy after surgical treatment: A systematic review. Seizure - European Journal of Epilepsy. 2021. Vol. 85, num. 95-101. ISSN 1059-1311. [consulted: 29 of June of 2026]. Available at: https://hdl.handle.net/2445/230149

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