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cc-by-nc-nd (c) Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular, 2021
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/191974

Isavuconazole prophylaxis against invasive fungal infections in allogeneic stem cell transplantation: a single-center experience

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Patients undergoing allogeneic stem cell transplantation (alloHCT) require profound immunosuppression is required to preserve graft function and prevent graft-versus host disease (GVHD), resulting in a high risk of infectious complications such as invasive fungal diseases (IFIs). Posaconazole is approved for primary antifungal prophylaxis alloHCT. However, posaconazole is associated with drug-drug interactions which may lead to relevant toxicities limiting it uses in hematological patients. Other triazoles, amphotericine B, and echinocandins can be used in patients at high risk of IFIs. However, there is less evidence supporting the efficacy of these drugs for the prevention of IFIs.

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QUERALT SALAS, Maria, MUSSETTI, Alberto, MUÑÓZ, Carme, ALBASANZ PUIG, Adaia, PATIÑO, Beatriz, JIMENEZ PRAT, Laura, GUDIOL GONZÁLEZ, Carlota, PARODY, Rocío, SUREDA, Anna. Isavuconazole prophylaxis against invasive fungal infections in allogeneic stem cell transplantation: a single-center experience. _Hematology_. Transfusion and Cell Therapy. Vol.  2021, núm. 44, pàgs. 3. [consulta: 27 de gener de 2026]. ISSN: 2531-1379. [Disponible a: https://hdl.handle.net/2445/191974]

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