Voltammetric determination of antihypertensive drug hydrochlorothiazide using screen-printed electrodes modified with L- glutamic acid

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dc.contributor.authorGonzález-Vargas, Camilo
dc.contributor.authorSerrano i Plana, Núria
dc.contributor.authorAriño Blasco, Cristina
dc.contributor.authorSalazar, Ricardo
dc.contributor.authorEsteban i Cortada, Miquel
dc.contributor.authorDíaz Cruz, José Manuel
dc.date.accessioned2017-10-02T07:24:34Z
dc.date.available2017-10-02T07:24:34Z
dc.date.issued2017-09-17
dc.date.updated2017-10-02T07:24:34Z
dc.description.abstractThis work deals with the development of screen-printed carbon electrodes modified with L-glutamic acid via two different approaches: electropolymerization (SPCE/PGA) and aryl diazonium electrochemical grafting (SPCE/EGA). SPCE/PGA and SPCE/EGA were analytically compared in the determination of hydrochlorothiazide (HCTZ) by differential pulse voltammetry. Both electrochemical characterization and analytical performance indicate that SPCE/EGA is a much better sensor for HCTZ. The detection and quantification limits were at the level of micromol L-1 with a very good linearity in the studied concentration range. In addition, the proposed SPCE/EGA was successfully applied for the determination of HCTZ in an anti-hypertensive drug with high reproducibility and good trueness.
dc.format.extent12 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec673372
dc.identifier.issn2227-9040
dc.identifier.urihttps://hdl.handle.net/2445/116084
dc.language.isoeng
dc.publisherMDPI
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/chemosensors5030025
dc.relation.ispartofChemosensors, 2017, vol. 5, num. 25, p. 1-12
dc.relation.urihttps://doi.org/10.3390/chemosensors5030025
dc.rightscc-by (c) González-Vargas, Camilo et al., 2017
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es
dc.sourceArticles publicats en revistes (Enginyeria Química i Química Analítica)
dc.subject.classificationAnàlisi electroquímica
dc.subject.classificationVoltametria
dc.subject.otherElectrochemical analysis
dc.subject.otherVoltammetry
dc.titleVoltammetric determination of antihypertensive drug hydrochlorothiazide using screen-printed electrodes modified with L- glutamic acid
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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