Files
Document type
ArticleVersion
Accepted versionPublication date
All rights reserved
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/168810
Lipids and physical function in older adults
Journal Title
Director/Tutor
Journal ISSN
Volume Title
Related resource
Abstract
PURPOSE OF REVIEW: Healthy aging is a public health priority. The maintenance of adequate physical function is recognized as a key element of healthy aging. In recent years, scientific evidence has increased concerning the ability of lipids, in particular omega 3 polyunsaturated fatty acids (n-3 PUFAs), to positively influence muscle and overall physical function in older patients. The article will critically review observational as well as intervention studies on this topic, and it will elucidate the potential biological mechanisms underlying the beneficial effects of n-3 PUFA on physical function. RECENT FINDINGS: Observational studies and clinical trials performed in healthy older patients and in older patients with chronic diseases mostly found positive effects of n-3 PUFA on muscle metabolism, muscle strength and in general physical function. SUMMARY: Although the use of n-3 PUFA might represent an important intervention to preserve physical function in older adults, several key questions still need to be answered. Above all, large randomized controlled trials should be performed to confirm the utility of n-3 PUFA as therapeutic agents to prevent and treat physical function decline in old age.
Subject
Subject (English)
Citation
Citation
CASAS AGUSTENCH, Patricia, CHERUBINI, Antonio and ANDRÉS LACUEVA, Ma. Cristina. Lipids and physical function in older adults. Current Opinion in Clinical Nutrition and Metabolic Care. 2016. Vol. 20, num. 1, pags. 16-25. ISSN 1363-1950. [consulted: 15 of August of 2026]. Available at: https://hdl.handle.net/2445/168810