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2024-06-12

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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/218661

REM sleep and neurodegeneration

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Recurs relacionat

https://doi.org/10.1111/jsr.14263

Resum

Several brainstem, subcortical and cortical areas are involved in the generation of rapid eye movement (REM) sleep. The alteration of these structures as a result of a neurodegenerative process may therefore lead to REM sleep anomalies. REM sleep behaviour disorder is associated with nightmares, dream-enacting behaviours and increased electromyographic activity in REM sleep. Its isolated form is a harbinger of synucleinopathies such as Parkinson's disease or dementia with Lewy bodies, and neuroprotective interventions are advocated. This link might also be present in patients taking antidepressants, with post-traumatic stress disorder, or with a history of repeated traumatic head injury. REM sleep likely contributes to normal memory processes. Its alteration has also been proposed to be part of the neuropathological changes occurring in Alzheimer's disease.

Matèries

Malaltia d'Alzheimer, Moviments oculars, Malaltia de Parkinson, Trastorns del son, Malalties neurodegeneratives

Matèries (anglès)

Alzheimer's disease, Eye movements, Parkinson's disease, Sleep disorders, Neurodegenerative Diseases

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

PÉREZ CARBONELL, Laura, IRANZO, Alex. REM sleep and neurodegeneration. _Journal of Sleep Research_. 2024. [consulta: 21 de gener de 2026]. ISSN: 0962-1105. [Disponible a: https://hdl.handle.net/2445/218661]

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