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T_1548756197munoz 3.pdf (1.46 MB)

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Book part

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Published version

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2018

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(c) Research Signpost, 2018
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/128109

Development of hybrid compounds to tackle Alzheimer’s disease

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http://hdl.handle.net/2445/128014
 http://hdl.handle.net/2445/115549

Abstract

Alzheimer’s disease (AD) is the main neurodegenerative disorder worldwide. Its pathogenesis involves a network where various mechanisms are interconnected. This complex pathological network makes it extremely challenging to find an efficacious treatment. Herein, we give an overview on the design of the so-called multi-target-directed ligands, i.e. compounds that concurrently hit several key pathogenic factors within the network, as a realistic option to tackle AD, with a particular emphasis on some structural classes of multitarget hybrids recently developed in our group.

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Podeu consultar el llibre complet a: http://hdl.handle.net/2445/128014

Subject

Desenvolupament de medicaments, Malaltia d'Alzheimer, Química farmacèutica

Subject (English)

Drug development, Alzheimer's disease, Pharmaceutical chemistry

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Llibres / Capítols de llibre (Farmacologia, Toxicologia i Química Terapèutica)

Citation

MUÑOZ-TORRERO LÓPEZ-IBARRA, Diego and PÉREZ AREALES, Francisco Javier. Development of hybrid compounds to tackle Alzheimer’s disease. Recent Advances in Pharmaceutical Sciences VIII. 2018. Vol. Editors: Diego Muñoz-Torrero, num. ISBN: 978-81-308-0579-5, pags. 43-58. [consulted: 8 of August of 2026]. Available at: https://hdl.handle.net/2445/128109

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