Miniatura

Fitxers

725474.pdf (1.58 MB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2022-09-29

Llicència de publicació

cc-by (c) Bermudo Gallaguet, Adrià et al., 2022
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/191010

Effects and mechanisms of mindfulness training and physical exercise on cognition, emotional wellbeing, and brain outcomes in chronic stroke patients: Study protocol of the MindFit project randomized controlled trial

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.3389/fnagi.2022.936077

Resum

Background: Post-stroke cognitive and emotional complications are frequent in the chronic stages of stroke and have important implications for the functionality and quality of life of those affected and their caregivers. Strategies such as mindfulness meditation, physical exercise (PE), or computerized cognitive training (CCT) may benefit stroke patients by impacting neuroplasticity and brain health. Materials and methods: One hundred and forty-one chronic stroke patients are randomly allocated to receive mindfulness-based stress reduction + CCT (n = 47), multicomponent PE program + CCT (n = 47), or CCT alone (n = 47). Interventions consist of 12-week home-based programs five days per week. Before and after the interventions, we collect data from cognitive, psychological, and physical tests, blood and stool samples, and structural and functional brain scans. Results: The effects of the interventions on cognitive and emotional outcomes will be described in intention-to-treat and per-protocol analyses. We will also explore potential mediators and moderators, such as genetic, molecular, brain, demographic, and clinical factors in our per-protocol sample. Discussion: The MindFit Project is a randomized clinical trial that aims to assess the impact of mindfulness and PE combined with CCT on chronic stroke patients' cognitive and emotional wellbeing. Furthermore, our design takes a multimodal biopsychosocial approach that will generate new knowledge at multiple levels of evidence, from molecular bases to behavioral changes. Clinical trial registration: www.ClinicalTrials.gov, identifier NCT04759950.

Matèries

Embòlia i trombosi cerebral, Malalties cerebrovasculars, Teràpia cognitiva basada en l'atenció plena, Exercici, Marcadors bioquímics

Matèries (anglès)

Cerebral embolism and thrombosis, Cerebrovascular disease, Mindfulness-based cognitive therapy, Exercise, Biochemical markers

Citació

Col·leccions

Articles publicats en revistes (Medicina)

Citació

BERMUDO GALLAGUET, Adrià, ARIZA GONZÁLEZ, Mar, DACOSTA-AGUAYO, Rosalia, AGUDELO, Daniela, CAMINS-VILA, Neus, BOLDÓ, Maria, CARRERA, Òscar, VIDAL, Sandra, FERRER-URIS, Blai, BUSQUETS FACIABÉN, Albert, VIA I GARCÍA, Marc, PERA, Guillem, CÁCERES, Cynthia, GOMIS, Meritxell, GARCÍA-MOLINA, Alberto, TORMOS, José maría, ARRABÉ, Ana, DIEZ, Gustavo, DURÀ MATA, Maria josé, TORÁN MONSERRAT, Pere, SORIANO RAYA, Juan josé, DOMÈNECH, Sira, PERERA LLUNA, Alexandre, ERICKSON, Kirk i., MATARÓ SERRAT, Maria. Effects and mechanisms of mindfulness training and physical exercise on cognition, emotional wellbeing, and brain outcomes in chronic stroke patients: Study protocol of the MindFit project randomized controlled trial. _Frontiers in Aging Neuroscience_. 2022. Vol. 14, núm. 14:936077, pàgs. 1-15. [consulta: 24 de gener de 2026]. ISSN: 1663-4365. [Disponible a: https://hdl.handle.net/2445/191010]

Exportar metadades

JSON - METS

Compartir registre