Amb motiu del tancament d'estiu, la validació de documents es reprendrà a partir del 28 d'agost de 2026. Disculpeu les molèsties.
Con motivo del cierre de verano, la validación de documentos se reanudará a partir del 28 de agosto de 2026. Disculpad las molestias
Due to the summer closure, document validation will resume starting August 28, 2026. We apologize for any inconvenience.

Fitxers

2023_AdvColIntSci_Lipidic_BlancoB.pdf (8.52 MB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2023-03-06

Llicència de publicació

cc by (c) Blanco Fernandez, Guillermo et al., 2023
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/197101

Lipidic lyotropic liquid crystals: Insights on biomedical applications

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1016/j.cis.2023.102867

Resum

Liquid crystals (LCs) possess unique physicochemical properties, translatable into a wide range of applications. To date, lipidic lyotropic LCs (LLCs) have been extensively explored in drug delivery and imaging owing to the capability to encapsulate and release payloads with different characteristics. The current landscape of lipidic LLCs in biomedical applications is provided in this review. Initially, the main properties, types, methods of fabrication and applications of LCs are showcased. Then, a comprehensive discussion of the main biomedical applications of lipidic LLCs accordingly to the application (drug and biomacromolecule delivery, tissue engi-neering and molecular imaging) and route of administration is examined. Further discussion of the main limi-tations and perspectives of lipidic LLCs in biomedical applications are also provided.Statement of significance: Liquid crystals (LCs) are those systems between a solid and liquid state that possess unique morphological and physicochemical properties, translatable into a wide range of biomedical applications. A short description of the properties of LCs, their types and manufacturing procedures is given to serve as a background to the topic. Then, the latest and most innovative research in the field of biomedicine is examined, specifically the areas of drug and biomacromolecule delivery, tissue engineering and molecular imaging. Finally, prospects of LCs in biomedicine are discussed to show future trends and perspectives that might be utilized. This article is an ampliation, improvement and actualization of our previous short forum article "Bringing lipidic lyotropic liquid crystal technology into biomedicine" published in TIPS.

Matèries

Cristalls líquids, Enginyeria de teixits, Sistemes d'alliberament de medicaments, Enginyeria biomèdica

Matèries (anglès)

Liquid crystals, Tissue engineering, Drug delivery systems, Biomedical engineering

Citació

Col·leccions

Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))

Citació

BLANCO FERNANDEZ, Guillermo, et al. Lipidic lyotropic liquid crystals: Insights on biomedical applications. Advances In Colloid And Interface Science. 2023. Vol. 313, num. 102867. ISSN 1873-3727. [consulted: 5 of August of 2026]. Available at: https://hdl.handle.net/2445/197101

Exportar metadades

JSON - METS

Compartir registre