Miniatura

Fitxers

656657.pdf (243.26 KB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2015-11-13

Tots els drets reservats

Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/96467

Red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients.

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

http://dx.doi.org/10.1039/c5fo00886g

Resum

This study evaluated the possible prebiotic effect of a moderate intake of red wine polyphenols on the modulation of the gut microbiota composition and the improvement in the risk factors for the metabolic syndrome in obese patients. Ten metabolic syndrome patients and ten healthy subjects were included in a randomized, crossover, controlled intervention study. After a washout period, the subjects consumed red wine and de-alcoholized red wine over a 30 day period for each. The dominant bacterial composition did not differ significantly between the study groups after the two red wine intake periods. In the metabolic syndrome patients, red wine polyphenols significantly increased the number of fecal bifidobacteria and Lactobacillus (intestinal barrier protectors) and butyrate-producing bacteria (Faecalibacterium prausnitzii and Roseburia) at the expense of less desirable groups of bacteria such as LPS producers (Escherichia coli and Enterobacter cloacae). The changes in gut microbiota in these patients could be responsible for the improvement in the metabolic syndrome markers. Modulation of the gut microbiota by using red wine could be an effective strategy for managing metabolic diseases associated with obesity.

Matèries

Intestins, Microbiologia, Polifenols, Vi negre, Síndrome metabòlica, Obesitat

Matèries (anglès)

Intestines, Microbiology, Polyphenols, Red wines, Metabolic syndrome, Obesity

Citació

Col·leccions

Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)

Citació

MORENO-INDIAS, Isabel, SÁNCHEZ-ALCOHOLADO, Lidia, PÉREZ-MARTÍNEZ, Pablo, ANDRÉS LACUEVA, Ma. cristina, CARDONA, Fernando, TINAHONES, Francisco j., QUEIPO ORTUÑO, María isabel. Red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients.. _Food & Function_. 2015. [consulta: 21 de gener de 2026]. ISSN: 2042-6496. [Disponible a: https://hdl.handle.net/2445/96467]

Exportar metadades

JSON - METS

Compartir registre