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Title: Apical periodontitis and diabetes mellitus type 2: a systematic review and meta-analysis
Author: Pérez-Losada, Flor de Liz
Estrugo Devesa, Albert
Castellanos Cosano, Lizett
Segura Egea, Juan José
López López, José, 1958-
Velasco Ortega, Eugenio
Keywords: Periodontitis
Ressenyes sistemàtiques (Investigació mèdica)
Systematic reviews (Medical research)
Issue Date: 17-Feb-2020
Publisher: MDPI
Abstract: Objective: investigate if there is an association between apical periodontitis and diabetes mellitus. Material and methods: a bibliographic search was performed on Medline/PubMed, Scopus and Cochrane databases using the keywords apical periodontitis and diabetes mellitus. Published papers written in English and performed on animals or humans were included. Meta-analysis was performed using the OpenMeta (analyst) tool for the statistical analysis. The variables analyzed were the prevalence of Apical Periodontitis (AP) among teeth and patients with Diabetes Mellitus (DM). Results: of the total studies found, only 21 met the inclusion criteria. Ten clinical studies on animals, ten studies on humans and a systematic review were included. Meta-analysis shows that the prevalence of teeth with apical periodontitis among patients with diabetes mellitus has an odds ratio of 1.166 corresponding to 507 teeth with AP + DM and 534 teeth with AP without DM. The prevalence of patients with AP and DM shows an odds ratio of 1.552 where 91 patients had AP + DM and 582 patients AP without DM. Conclusion: scientific evidence suggests that there could be a common physiopathological factor between apical periodontitis and diabetes mellitus but more prospective studies are needed to investigate the association between these two diseases.
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It is part of: Journal of Clinical Medicine, 2020, vol. 9, num. 2, p. ES40
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ISSN: 2077-0383
Appears in Collections:Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (Odontoestomatologia)

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