Standardization procedure for flow cytometry data harmonization in prospective multicenter studies

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dc.contributor.authorLe Lann, Lucas
dc.contributor.authorJouve, Pierre Emmanuel
dc.contributor.authorAlarcón Riquelme, Marta
dc.contributor.authorJamin, Christophe
dc.contributor.authorPers, Jacques-Olivier
dc.contributor.authorPRECISESADS Flow Cytometry Study Group
dc.contributor.authorPRECISESADS Clinical Consortium
dc.contributor.authorCervera i Segura, Ricard, 1960-
dc.date.accessioned2021-05-04T20:25:09Z
dc.date.available2021-05-04T20:25:09Z
dc.date.issued2020-07-14
dc.date.updated2021-05-04T20:25:09Z
dc.description.abstractOne of the most challenging objective for clinical cytometry in prospective multicenter immunomonitoring trials is to compare frequencies, absolute numbers of leukocyte populations and further the mean fluorescence intensities of cell markers, especially when the data are generated from different instruments. Here, we describe an innovative standardization workflow to compare all data to carry out any large-scale, prospective multicentric flow cytometry analysis whatever the duration, the number or type of instruments required for the realization of such projects.
dc.format.extent8 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec708153
dc.identifier.issn2045-2322
dc.identifier.pmid32665668
dc.identifier.urihttps://hdl.handle.net/2445/177015
dc.language.isoeng
dc.publisherNature Publishing Group
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1038/s41598-020-68468-3
dc.relation.ispartofScientific Reports, 2020, vol. 10, num. 1, p. 11567
dc.relation.urihttps://doi.org/10.1038/s41598-020-68468-3
dc.rightscc-by (c) Le Lann, Lucas et al., 2020
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es
dc.sourceArticles publicats en revistes (Medicina)
dc.subject.classificationCitometria de fluxe
dc.subject.classificationLeucòcits
dc.subject.otherFlow cytometry
dc.subject.otherLeucocytes
dc.titleStandardization procedure for flow cytometry data harmonization in prospective multicenter studies
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))