Proximity-induced pharmacology for amyloid-related diseases<br />
| dc.contributor.author | Bertran-Mostazo, Andrea | |
| dc.contributor.author | Putriute, Gabrielé | |
| dc.contributor.author | Álvarez-Berbel, Irene | |
| dc.contributor.author | Busquets i Viñas, Ma. Antonia | |
| dc.contributor.author | Galdeano Cantador, Carlos | |
| dc.contributor.author | Espargaró Colomé, Alba | |
| dc.contributor.author | Sabaté Lagunas, Raimon | |
| dc.date.accessioned | 2024-10-21T10:49:16Z | |
| dc.date.available | 2024-10-21T10:49:16Z | |
| dc.date.issued | 2024-03-04 | |
| dc.date.updated | 2024-10-21T10:49:16Z | |
| dc.description.abstract | <p>Proximity-induced pharmacology (PIP) for amyloid-related diseases is a cutting-edge</p><p>approach to treating conditions such as Alzheimer’s disease and other forms of dementia. By bringing</p><p>small molecules close to amyloid-related proteins, these molecules can induce a plethora of effects</p><p>that can break down pathogenic proteins and reduce the buildup of plaques. One of the most</p><p>promising aspects of this drug discovery modality is that it can be used to target specific types of</p><p>amyloid proteins, such as the beta-amyloid protein that is commonly associated with Alzheimer’s</p><p>disease. This level of specificity could allow for more targeted and effective treatments. With ongoing</p><p>research and development, it is hoped that these treatments can be refined and optimized to provide</p><p>even greater benefits to patients. As our understanding of the underlying mechanisms of these</p><p>diseases continues to grow, proximity-induced pharmacology treatments may become an increasingly</p><p>important tool in the fight against dementia and other related conditions.</p> | |
| dc.format.extent | 1 p. | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.idgrec | 746915 | |
| dc.identifier.issn | 2073-4409 | |
| dc.identifier.uri | https://hdl.handle.net/2445/215920 | |
| dc.language.iso | eng | |
| dc.publisher | MDPI | |
| dc.relation.isformatof | Reproducció del document publicat a: https://doi.org/10.3390/cells13050449 | |
| dc.relation.ispartof | Cells, 2024, vol. 13 | |
| dc.relation.uri | https://doi.org/10.3390/cells13050449 | |
| dc.rights | cc-by (c) Bertran-Mostazo, A. et al., 2024 | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.source | Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica) | |
| dc.subject.classification | Malalties neurodegeneratives | |
| dc.subject.classification | Amiloïdosi | |
| dc.subject.classification | Disseny de medicaments | |
| dc.subject.other | Neurodegenerative Diseases | |
| dc.subject.other | Amyloidosis | |
| dc.subject.other | Drug design | |
| dc.title | Proximity-induced pharmacology for amyloid-related diseases<br /> | |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/publishedVersion |
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