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cc-by-nc-nd (c) Elsevier, 2020
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/168021

Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out

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Despite wide antiretroviral scale-up during the past two decades resulting in declining new infections and mortality globally, HIV-associated tuberculosis remains as a major public health concern. Tuberculosis is the leading HIV-associated opportunistic infection and the main cause of death globally and, particularly, in resource-limited settings. Several challenges exist regarding diagnosis, global implementation of latent tuberculosis treatment, management of active tuberculosis, delivery of optimal patient-centered TB and HIV prevention and care in high burden countries. In this article we review the advances on pathogenesis, diagnosis, and treatment after nearly two decades of global roll-out of antiretroviral therapy and discuss the current challenges for the global control of tuberculosis-HIV co-infection.

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LETANG, Emilio, et al. Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out. Archivos de Bronconeumologia. 2020. Vol. 56, num. 7, pags. 446-454. ISSN 0300-2896. [consulted: 16 of June of 2026]. Available at: https://hdl.handle.net/2445/168021

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