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CARM1 and BAF155: an example of how chromatin remodeling factors can be relocalized and contribute to cancer

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dc.contributor.authorStefansson, Olafur A.
dc.contributor.authorEsteller, Manel, 1968-
dc.date.accessioned2018-11-12T09:34:52Z
dc.date.available2018-11-12T09:34:52Z
dc.date.issued2014-05-19
dc.date.updated2018-11-12T09:34:52Z
dc.description.abstractIn a recent article, Wang and colleagues reported the discovery of a mechanism by which CARM1 regulates the genomic localization of BAF155 (a SWI/SNF subunit involved in chromatin remodeling) through post-translational methylation at R1064 arginine residues. This modification leads to the relocalization of BAF155-containing SWI/SNF complexes to regions containing genes involved in the Myc oncogenic pathway. The results presented are evidence that these interactions constitute a mechanism by which the BAF155 chromatin remodeling factor contributes to cancer.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec662732
dc.identifier.issn1465-542X
dc.identifier.pmid25927994
dc.identifier.urihttps://hdl.handle.net/2445/126004
dc.language.isoeng
dc.publisherBioMed Central
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1186/bcr3657
dc.relation.ispartofBreast Cancer Research, 2014, vol. 16, num. 3, p. 307
dc.relation.urihttps://doi.org/10.1186/bcr3657
dc.rightscc-by (c) Stefansson, Olafur A. et al., 2014
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es
dc.sourceArticles publicats en revistes (Ciències Fisiològiques)
dc.subject.classificationCàncer
dc.subject.classificationMetàstasi
dc.subject.classificationCromatina
dc.subject.otherCancer
dc.subject.otherMetastasis
dc.subject.otherChromatin
dc.titleCARM1 and BAF155: an example of how chromatin remodeling factors can be relocalized and contribute to cancer
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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