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2014-05-19

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cc-by (c) Stefansson, Olafur A. et al., 2014
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/126004

CARM1 and BAF155: an example of how chromatin remodeling factors can be relocalized and contribute to cancer

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https://doi.org/10.1186/bcr3657

Abstract

In a recent article, Wang and colleagues reported the discovery of a mechanism by which CARM1 regulates the genomic localization of BAF155 (a SWI/SNF subunit involved in chromatin remodeling) through post-translational methylation at R1064 arginine residues. This modification leads to the relocalization of BAF155-containing SWI/SNF complexes to regions containing genes involved in the Myc oncogenic pathway. The results presented are evidence that these interactions constitute a mechanism by which the BAF155 chromatin remodeling factor contributes to cancer.

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Càncer, Metàstasi, Cromatina

Subject (English)

Cancer, Metastasis, Chromatin

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Articles publicats en revistes (Ciències Fisiològiques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citation

STEFANSSON, Olafur A. and ESTELLER, Manel. CARM1 and BAF155: an example of how chromatin remodeling factors can be relocalized and contribute to cancer. Breast Cancer Research. 2014. Vol. 16, num. 3, pags. 307. ISSN 1465-542X. [consulted: 12 of June of 2026]. Available at: https://hdl.handle.net/2445/126004

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