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Article

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2019-08-01

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cc-by-nc-nd (c) Taiwan Society of Microbiology, 2019
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/163507

Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count

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https://doi.org/10.1016/j.jmii.2018.07.007

Abstract

Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137-0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = −0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found.

Subject

Cèl·lules T, VIH (Virus), Micro RNAs, Marcadors bioquímics

Subject (English)

T cells, HIV (Viruses), MicroRNAs, Biochemical markers

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citation

RUIZ-DE-LEON, Maria J., et al. Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count. Journal of Microbiology Immunology and Infection. 2019. Vol. 52, num. 4, pags. 667-671. ISSN 1684-1182. [consulted: 10 of June of 2026]. Available at: https://hdl.handle.net/2445/163507

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