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Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count

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dc.contributor.authorRuiz-de-Leon, Maria J.
dc.contributor.authorJimenez-Sousa, Maria A.
dc.contributor.authorMoreno, Santiago
dc.contributor.authorGarcia, Marcial
dc.contributor.authorGutierrez-Rivas, Monica
dc.contributor.authorLeón García, Agathe
dc.contributor.authorMontero-Alonso, Marta
dc.contributor.authorGonzalez-Garcia, Juan
dc.contributor.authorResino, Salvador
dc.contributor.authorRallón, Norma
dc.contributor.authorBenito, José M.
dc.contributor.authorVallejo, Alejandro
dc.contributor.authorECRIS Network integrated in the Spanish AIDS Resea
dc.date.accessioned2020-06-01T21:29:37Z
dc.date.available2020-06-01T21:29:37Z
dc.date.issued2019-08-01
dc.date.updated2020-06-01T21:29:38Z
dc.description.abstractExosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137-0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = −0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found.
dc.format.extent5 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec693494
dc.identifier.issn1684-1182
dc.identifier.urihttps://hdl.handle.net/2445/163507
dc.language.isoeng
dc.publisherElsevier
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.jmii.2018.07.007
dc.relation.ispartofJournal of Microbiology Immunology and Infection, 2019, vol. 52, num. 4, p. 667-671
dc.relation.urihttps://doi.org/10.1016/j.jmii.2018.07.007
dc.rightscc-by-nc-nd (c) Taiwan Society of Microbiology, 2019
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es
dc.sourceArticles publicats en revistes (Medicina)
dc.subject.classificationCèl·lules T
dc.subject.classificationVIH (Virus)
dc.subject.classificationMicro RNAs
dc.subject.classificationMarcadors bioquímics
dc.subject.otherT cells
dc.subject.otherHIV (Viruses)
dc.subject.otherMicroRNAs
dc.subject.otherBiochemical markers
dc.titleLower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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