A genome-wide association study of marginal zone lymphoma shows association to the HLA region

Vista senzilla d'ítem
dc.contributor.authorVijai, Joseph
dc.contributor.authorWang, Zhaoming
dc.contributor.authorBerndt, Sonja I.
dc.contributor.authorSkibola, Christine F.
dc.contributor.authorSlager, Susan L.
dc.contributor.authorSanjosé Llongueras, Silvia de
dc.contributor.authorMelbye, Mads
dc.contributor.authorGlimelius, Bengt
dc.contributor.authorBracci, Paige M.
dc.contributor.authorConde, Lucía
dc.contributor.authorBirmann, Brenda M.
dc.contributor.authorDiver, W. Ryan
dc.contributor.authorVajdic, Claire M.
dc.contributor.authorArmstrong, Bruce K.
dc.contributor.authorKricker, Anne
dc.contributor.authorZheng, Tongzhang
dc.contributor.authorHolford, Theodore R.
dc.contributor.authorSeveri, Gianluca
dc.contributor.authorVineis, Paolo
dc.contributor.authorFerri, Giovanni M.
dc.contributor.authorRicco, Rosalia
dc.contributor.authorMiligi, Lucia
dc.contributor.authorClavel, Jacqueline
dc.contributor.authorGiovannucci, Edward L.
dc.contributor.authorKraft, Peter
dc.contributor.authorVirtamo, Jarmo
dc.contributor.authorSmith, Alex
dc.contributor.authorKane, Eleanor
dc.contributor.authorRoman, Eve
dc.contributor.authorChiu, Brian C. H.
dc.contributor.authorFraumeni, Joseph F.
dc.contributor.authorWu, Xifeng
dc.contributor.authorCerhan, James R.
dc.contributor.authorOffit, Kenneth
dc.contributor.authorChanock, Stephen J.
dc.contributor.authorRothman, Nathaniel
dc.contributor.authorNieters, Alexandra
dc.contributor.authorWang, Sophia S.
dc.contributor.authorBrooks-Wilson, Angela R.
dc.contributor.authorLan, Qing
dc.contributor.authorBakker, Paul I. W. de
dc.contributor.authorVermeulen, Roel C. H.
dc.contributor.authorPortlock, Carol
dc.contributor.authorAnsell, Stephen M.
dc.contributor.authorLink, Brian K.
dc.contributor.authorRiby, Jacques
dc.contributor.authorNorth, Kari E.
dc.contributor.authorGu, Jian
dc.contributor.authorHjalgrim, Henrik
dc.contributor.authorCozen, Wendy
dc.contributor.authorBecker, Nikolaus
dc.contributor.authorTeras, Lauren R.
dc.contributor.authorSpinelli, John J.
dc.contributor.authorTurner, Jenny
dc.contributor.authorZhang, Yawei
dc.contributor.authorPurdue, Mark P.
dc.contributor.authorGiles, Graham G.
dc.contributor.authorKelly, Rachel S.
dc.contributor.authorZeleniuch-Jacquotte, Anne
dc.contributor.authorEnnas, Maria Grazia
dc.contributor.authorMonnereau, Alain
dc.contributor.authorBertrand, Kimberly A.
dc.contributor.authorAlbanes, Demetrius
dc.contributor.authorLightfoot, Tracy
dc.contributor.authorYeager, Meredith
dc.contributor.authorChung, Charles C.
dc.contributor.authorBurdett, Laurie
dc.contributor.authorHutchinson, Amy
dc.contributor.authorLawrence, Charles
dc.contributor.authorMontalvan, Rebecca
dc.contributor.authorLiang, Liming
dc.contributor.authorHuang, Jinyan
dc.contributor.authorMa, Baoshan
dc.contributor.authorVillano, Danylo J.
dc.contributor.authorMaria, Ann
dc.contributor.authorCorines, Marina
dc.contributor.authorThomas, Tinu
dc.contributor.authorNovak, Anne J.
dc.contributor.authorDogan, Ahmet
dc.contributor.authorLiebow, Mark
dc.contributor.authorThompson, Carrie A.
dc.contributor.authorWitzig, Thomas E.
dc.contributor.authorHabermann, Thomas M.
dc.contributor.authorWeiner, George J.
dc.contributor.authorSmith, Martyn T.
dc.contributor.authorHolly, Elizabeth A.
dc.contributor.authorJackson, Rebecca D. J.
dc.contributor.authorTinker, Lesley F.
dc.contributor.authorYe, Yuanqing
dc.contributor.authorAdami, Hans-Olov
dc.contributor.authorSmedby, Karin E.
dc.contributor.authorRoos, Anneclaire J. De
dc.contributor.authorHartge, Patricia
dc.contributor.authorMorton, Lindsay M.
dc.contributor.authorSeverson, Richard K.
dc.contributor.authorBenavente, Yolanda
dc.contributor.authorBoffetta, Paolo
dc.contributor.authorBrennan, Paul
dc.contributor.authorForetova, Lenka
dc.contributor.authorMaynadié, Marc
dc.contributor.authorMcKay, James D.
dc.contributor.authorStaines, Anthony
dc.date.accessioned2018-11-16T09:44:21Z
dc.date.available2018-11-16T09:44:21Z
dc.date.issued2015-01-08
dc.date.updated2018-07-24T12:35:07Z
dc.description.abstractMarginal zone lymphoma (MZL) is the third most common subtype of B-cell non-Hodgkin lymphoma. Here we perform a two-stage GWAS of 1,281 MZL cases and 7,127 controls of European ancestry and identify two independent loci near BTNL2 (rs9461741, P - 3.95 x 10(-15)) and HLA-B (rs2922994, P - 2.43 x 10(-9)) in the HLA region significantly associated with MZL risk. This is the first evidence that genetic variation in the major histocompatibility complex influences MZL susceptibility.
dc.format.mimetypeapplication/pdf
dc.identifier.pmid25569183
dc.identifier.urihttps://hdl.handle.net/2445/126171
dc.language.isoeng
dc.publisherNature Publishing Group
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1038/ncomms6751
dc.relation.ispartofNature Communications, 2015, vol. 6
dc.relation.urihttps://doi.org/10.1038/ncomms6751
dc.rightscc by (c) Vijai et al., 2015
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.sourceArticles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
dc.subject.classificationMalaltia de Hodgkin
dc.subject.classificationCèl·lules B
dc.subject.otherHodgkin's disease
dc.subject.otherB cells
dc.titleA genome-wide association study of marginal zone lymphoma shows association to the HLA region
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

Fitxers

Paquet original

Mostrant 1 - 1 de 1
Miniatura
Nom:
VijaiJ.pdf
Mida:
528.5 KB
Format:
Adobe Portable Document Format
Descarregar

Col·leccions

Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))