Clinical Implications of Genomic Profile in Waldenström Macroglobulinemia

Vista senzilla d'ítem
dc.contributor.authorMoreno, D. F.
dc.contributor.authorFernández de Larrea Rodríguez, Carlos José
dc.date.accessioned2024-02-06T11:44:08Z
dc.date.available2024-06-27T05:10:13Z
dc.date.issued2023-08-01
dc.date.updated2024-02-06T10:14:44Z
dc.description.abstractWith the increasing availability of sequencing techniques and new polymerase chain reaction-based methods, data regarding the genomic profile of Waldenström macroglobulinemia (WM) are being continuously analyzed and reproduced. MYD88 and CXCR4 mutations are highly prevalent in all the stages of WM, including the early IgM monoclonal gammopathy of undetermined significance or a more advanced stage, such as smoldering WM. Thus, there is a need to define genotypes before starting either standard treatment regimens or clinical trials. Here, we review the genomic profile of WM and its clinical implications while focusing on recent advances.Copyright © 2023 Elsevier Inc. All rights reserved.ca
dc.format.extent15 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idimarina9354886
dc.identifier.issn0889-8588
dc.identifier.pmid37211494
dc.identifier.urihttps://hdl.handle.net/2445/207222
dc.language.isoengca
dc.publisherElsevierca
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.hoc.2023.04.002
dc.relation.ispartofHematology-Oncology Clinics Of North America, 2023, vol. 37, num. 4, p. 659-670
dc.relation.urihttps://doi.org/10.1016/j.hoc.2023.04.002
dc.rightscc by-nc-nd (c) Elsevier, 2024
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.sourceArticles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
dc.subject.classificationLimfomes
dc.subject.classificationMutació (Biologia)
dc.subject.otherLymphomas
dc.subject.otherMutation (Biology)
dc.titleClinical Implications of Genomic Profile in Waldenström Macroglobulinemiaca
dc.typeinfo:eu-repo/semantics/articleca
dc.typeinfo:eu-repo/semantics/publishedVersion

Fitxers

Paquet original

Mostrant 1 - 1 de 1
Miniatura
Nom:
CH0002_de+Larrea_v2.pdf
Mida:
173.83 KB
Format:
Adobe Portable Document Format
Descarregar

Col·leccions

Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)