Document type
ArticleVersion
Published versionPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/126526
New transcription regulatory mechanisms of latent HIV LTR
Journal Title
Director/Tutor
Additional contribution
Journal ISSN
Volume Title
Abstract
Despite the effectiveness of antiretroviral medication, the
HIV virus persists in resting memory T cells of infected
patients in a latent state, providing the main impediment
to eradication of the virus. We are interested in identifying
the molecular mechanism responsible for the establishment
and maintenance of HIV latency and its re-activation.
We recently used a cell system reflecting HIV latency
in my lab to determine the high resolution nucleosomal
landscape of the latent HIV LTR and examine its dynamic
changes upon re-activation (Rafati et al., Nov 2011 PLoS
Biology)...
Related resource
Subject
Subject (English)
Citation
Citation
RAFATI, Haleh, et al. New transcription regulatory mechanisms of latent HIV LTR. Retrovirology. 2012. Vol. 9, num. 1, pags. O3. [consulted: 12 of October of 2026]. Available at: https://hdl.handle.net/2445/126526