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A Novel, Extremely Bioavailable Cocrystal of Pterostilbene

dc.contributor.authorBofill, Lídia
dc.contributor.authorBarbas Cañero, Rafael
dc.contributor.authorSande, Dafne de
dc.contributor.authorFont Bardia, Ma. Mercedes
dc.contributor.authorRàfols Llach, Clara
dc.contributor.authorAlbertí, Joan
dc.contributor.authorProhens López, Rafael
dc.date.accessioned2022-02-25T10:57:52Z
dc.date.available2022-03-03T06:10:26Z
dc.date.issued2021-03-03
dc.date.updated2022-02-25T10:57:52Z
dc.description.abstractNew multicomponent solid forms of the nutraceutical pterostilbene have been discovered and characterized through experimental cocrystal screening. Among the coformers tested, picolinic acid formed a cocrystal with a 10-fold enhancement of oral bioavailability in rats, which converts the new cocrystal into a very promising candidate for new formulations of pterostilbene with improved performance.
dc.format.extent27 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec710755
dc.identifier.issn1528-7483
dc.identifier.urihttps://hdl.handle.net/2445/183529
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1021/acs.cgd.0c01716
dc.relation.ispartofCrystal Growth & Design, 2021, vol. 21, num. 4, p. 2315-2323
dc.relation.urihttps://doi.org/10.1021/acs.cgd.0c01716
dc.rights(c) American Chemical Society , 2021
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Mineralogia, Petrologia i Geologia Aplicada)
dc.subject.classificationCristal·lografia
dc.subject.otherCrystallography
dc.titleA Novel, Extremely Bioavailable Cocrystal of Pterostilbene
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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