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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/222911
Exercici físic i resistència a la insulina associada a l'obesitat
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[eng] There has been a recent increase in population obesity, and the percentage of people with this pathology is expected to increase in the next ten years. In a state of obesity, there is a dysfunction in the insulin signaling pathway and it is generated a resistance to this hormone. Insulin regulates energy metabolism by promoting the uptake and storage of glucose. Insulin resistance is the consequence of the inability of insulin to activate hormone signaling and the consequent metabolic regulation. Different mechanisms induce this insulin resistance during obesity: mitochondrial dysfunction and oxidative stress, endoplasmic reticulum stress,
inflammation and autophagy. Regular physical exercise, especially the combination of aerobic and strength exercise, improves insulin sensitivity. So does AMP-activated protein kinase (AMPK), that it is induced by physical exercise and medication. In other words, physical exercise is an essential tool in the prevention and treatment of obesity-associated insulin resistance. The aim of this review is to define the mechanisms by which physical exercise can be used as a therapeutic tool to improve obesity-associated insulin resistance.
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Treballs Finals de Grau de Nutrició Humana i Dietètica, Facultat de Farmàcia i Ciències de l'Alimentació, Campus de l'Alimentació de Torribera, Universitat de Barcelona. Curs: 2024-2025. Tutor: Carme Caelles Franch
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ORTIGOSA LAGUNA, Aina. Exercici físic i resistència a la insulina associada a l'obesitat. [consulta: 3 de desembre de 2025]. [Disponible a: https://hdl.handle.net/2445/222911]