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Reproducibility of optical coherence tomography airway imaging

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Optical coherence tomography (OCT) is a promising imaging technique to evaluate small airway remodeling. However, the short-term insertion-reinsertion reproducibility of OCT for evaluating the same bronchial pathway has yet to be established. We evaluated 74 OCT data sets from 38 current or former smokers twice within a single imaging session. Although the overall insertion-reinsertion airway wall thickness (WT) measurement coefficient of variation (CV) was moderate at 12%, much of the variability between repeat imaging was attributed to the observer; CV for repeated measurements of the same airway (intra-observer CV) was 9%. Therefore, reproducibility may be improved by introduction of automated analysis approaches suggesting that OCT has potential to be an in-vivo method for evaluating airway remodeling in future longitudinal and intervention studies. (C) 2015 Optical Society of America

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KIRBY, Miranda, OHTANI, Keishi, NICKENS, Taylor, LOPEZ LISBONA, Rosa maria, LEE, Anthony m. d., SHAIPANICH, Tawimas, LANE, Pierre, MACAULAY, Calum, LAM, Stephen, COXSON, Harvey o.. Reproducibility of optical coherence tomography airway imaging. _Biomedical Optics Express_. 2015. Vol. 6, núm. 11, pàgs. 4365-4377. [consulta: 22 de febrer de 2026]. [Disponible a: https://hdl.handle.net/2445/124213]

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